Limited added value of laboratory monitoring in thiopurine maintenance monotherapy in inflammatory bowel disease patients.

Author: , BoumaGerd, DijkstraGerard, KreijneJoany E, VoskuilMichiel D, WestRachel, de BoerNanne K, de JongDirk J, de VeerRozanne C, de VriesAnnemarie C, van MoorselSofia A W, van der WoudeC Janneke

Paper Details 
Original Abstract of the Article :
BACKGROUND: To timely detect myelotoxicity and hepatotoxicity, laboratory monitoring at 3-month intervals is advised throughout thiopurine maintenance treatment for IBD. However, reported incidence rates of myelotoxicity and hepatotoxicity in maintenance treatment are low. AIM: To assess incidence ...See full text at original site
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引用元:
https://doi.org/10.1111/apt.15734

データ提供:米国国立医学図書館(NLM)

Laboratory Monitoring in Thiopurine Maintenance Monotherapy for IBD: Is it Worth It?

Navigating the vast and complex desert of inflammatory bowel disease (IBD) research requires careful consideration of every detail. This study examines the necessity of frequent laboratory monitoring for patients undergoing thiopurine maintenance therapy. This research is like exploring a desert landscape for hidden sources of water – we want to ensure that our patients are well-hydrated, but are we monitoring their levels too frequently?

Limited Added Value of Frequent Monitoring

The researchers found that severe laboratory toxicity is uncommon in patients who have been on thiopurine monotherapy for at least a year. This means that frequent monitoring might not be as crucial after the initial year of treatment. It’s like finding a reliable wellspring in the desert, so we can relax a little and conserve our resources, knowing the water will be there when we need it.

Adjusting Monitoring Frequencies for Optimal Care

The study suggests that we can adjust monitoring frequencies for IBD patients on thiopurine maintenance therapy. This is like finding a new, more efficient route through the desert, allowing us to conserve resources and focus on the areas that truly need attention. While monitoring is still important, we can be more strategic in our approach and provide personalized care based on individual patient needs. This means a more efficient and targeted approach to ensure the well-being of our patients.

Dr. Camel's Conclusion

This study provides valuable insights into the optimal monitoring strategies for IBD patients on thiopurine maintenance therapy. It’s like finding a hidden oasis of knowledge that helps us optimize our treatment plans and minimize unnecessary burdens on our patients. Remember, this study focuses on patients who have been on thiopurine for at least a year. It’s always important to consult with your doctor to determine the best monitoring schedule for your individual needs.

Date :
  1. Date Completed 2020-11-23
  2. Date Revised 2020-11-23
Further Info :

Pubmed ID

32342997

DOI: Digital Object Identifier

10.1111/apt.15734

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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