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Long-term Castration-related Outcomes in Patients With High-risk Localized Prostate Cancer Treated With Androgen Deprivation Therapy With or Without Docetaxel and Estramustine in the UNICANCER GETUG-12 Trial.

Author: AlbigesLaurence, BaciarelloGiulia, BlanchardPierre, BossetPierre-Olivier, BossiAlberto, ColombaEmeline, DumontClément, FizaziKarim, LavaudPernelle, LoriotYohann, MassardChristophe, NenanSoazig

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study investigated whether adding chemotherapy to a standard treatment for prostate cancer would affect long-term side effects. The study found that adding chemotherapy did not increase the risk of long-term side effects.
Paper Details　
Original Abstract of the Article :
Neoadjuvant chemotherapy with docetaxel and estramustine (DE) significantly improved relapse-free survival in patients with high-risk localized prostate cancer treated with androgen deprivation therapy (ADT) for 3 years and a local treatment in the GETUG-12 phase III trial. We sought to explore whet...See full text at original site
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引用元：
https://doi.org/10.1016/j.clgc.2020.03.017

データ提供：米国国立医学図書館（NLM）

Prostate Cancer Treatment: A Desert of Complexities

Prostate cancer is like a treacherous sandstorm, a serious health condition that requires careful management. This study is like a scientific expedition, exploring the long-term effects of different treatment strategies for high-risk localized prostate cancer.

The researchers investigated the impact of adding docetaxel and estramustine (DE) to androgen deprivation therapy (ADT) for patients with high-risk prostate cancer. They found that DE significantly improved relapse-free survival but also explored the potential for long-term side effects. This is like navigating a desert landscape, carefully considering the trade-offs between the benefits and risks of different paths.

Navigating the Desert of Prostate Cancer Treatment

Prostate cancer treatment is a complex journey, like navigating a vast and unforgiving desert. This study provides valuable insights into the effectiveness of different treatment options, helping healthcare providers to make informed decisions about the best path for their patients.

Living with Prostate Cancer: Finding Hope and Resilience

Prostate cancer can be a challenging diagnosis, but with the right care and support, patients can find strength and resilience. This study offers a deeper understanding of the potential benefits and risks of different treatment options, helping patients and healthcare providers navigate the desert of prostate cancer with greater confidence.

Dr.Camel's Conclusion

This study highlights the importance of carefully evaluating the long-term effects of different treatment strategies for prostate cancer. It's a reminder that even in the most challenging of deserts, there are always possibilities for finding relief and recovery. Remember, with knowledge and perseverance, we can find our way through any obstacle and emerge stronger and healthier.
Date :
  1. Date Completed 2021-08-18
  2. Date Revised 2021-08-18
Further Info :

Pubmed ID

32349927

DOI: Digital Object Identifier

10.1016/j.clgc.2020.03.017

Related Literature

Article Analysis
・Side Effects of estramustine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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