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Potential Patient-Reported Toxicities With Disulfiram Treatment in Late Disseminated Lyme Disease.
Author: GascanHugues, GhozziRaouf, TrautmannAlain
Original Abstract of the Article :
Recently, disulfiram has been proposed as a promising treatment for people suffering from persistent symptoms of Lyme Disease. Disulfiram has several distinct molecular targets. The most well-known is alcohol dehydrogenase, a key enzyme for detoxifying the organism after alcohol ingestion. Other tar...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184924/
データ提供:米国国立医学図書館(NLM)
Disulfiram: A Controversial Treatment for Lyme Disease
Lyme disease, a tick-borne illness that can cause a wide range of symptoms, is like a mysterious desert mirage, often difficult to diagnose and treat. This study explores the potential use of disulfiram, a medication traditionally used for alcohol dependence, as a treatment for late-stage Lyme disease.
Potential Benefits and Risks
The study highlights the potential benefits of disulfiram, while also cautioning about the risks associated with its use. Disulfiram, like a double-edged sword in the desert, has multiple molecular targets, some of which could lead to adverse effects.
Patient-Reported Outcomes: A Crucial Factor
The study emphasizes the importance of patient-reported outcomes in the evaluation of disulfiram for Lyme disease. Gathering information directly from patients, like listening to the whispers of the desert wind, can provide crucial insights into the effectiveness and safety of treatments.
Dr. Camel's Conclusion
This study underscores the need for careful consideration and further research before promoting disulfiram as a treatment for Lyme disease. The potential benefits must be weighed against the risks, particularly given the limited evidence and the importance of patient-reported outcomes. As we continue to explore the vast and enigmatic desert of Lyme disease, we must strive to develop safe and effective therapies based on rigorous scientific evidence.
Date :
- Date Completed n.d.
- Date Revised 2020-09-28
Further Info :
Related Literature
English
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