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Insilico analysis of marine indole alkaloids for design of adenosine A2A receptor antagonist.
Author: BhusnuareOmprakash, ChoudhariPrafulla, LonikarNitin
Original Abstract of the Article :
Neurological disease is the disease associated with most of geriatric population in the world. The diseases like Alzheimer's disease and Parkinson's disease are associated with the change in the life style in current era. Treatment of these diseases normally focused on the agents which can able to m...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1080/07391102.2020.1765874
データ提供:米国国立医学図書館(NLM)
Marine Indole Alkaloids: A Treasure Trove for Neurological Disease Treatment
Neurological diseases, such as Alzheimer's and Parkinson's, are a growing concern in our aging population. This study delves into the vast ocean of marine natural products, exploring their potential as therapeutic agents for these debilitating conditions. The authors conducted a virtual screening of marine indole alkaloids, molecules found in marine organisms, to identify potential candidates for adenosine A2A receptor antagonists.
The researchers, like treasure hunters scouring the seabed, identified several promising candidates with excellent binding affinity to the adenosine A2A receptor. These marine alkaloids, such as topsentin C and 6'-debromohamacanthin, hold significant potential for developing novel treatments for neurological diseases. The study's findings provide a promising path for exploring the vast and untapped therapeutic potential of marine natural products. These molecules, like pearls discovered deep beneath the waves, could revolutionize the treatment of neurological diseases.
A New Frontier in Neurological Disease Treatment
The study's findings suggest that marine indole alkaloids could hold the key to developing novel treatments for neurological diseases. The identification of these promising candidates with excellent binding affinity to the adenosine A2A receptor offers a beacon of hope for patients seeking effective therapies.
Exploring the Ocean's Bounty
The vast and largely unexplored world of marine natural products offers a treasure trove of potential therapeutic agents. This study's findings highlight the importance of exploring these natural resources for developing new and innovative treatments for neurological diseases. The ocean's bounty, like a rich vein of gold, could hold the key to improving the lives of millions affected by these debilitating conditions.
Dr. Camel's Conclusion
This research paves the way for exploring the therapeutic potential of marine indole alkaloids, offering a promising new frontier in the treatment of neurological diseases. The vast and untapped resources of the marine environment hold the key to unlocking new and innovative treatments, allowing us to dive deeper into the ocean of hope for patients battling these debilitating conditions.
Date :
- Date Completed 2021-07-02
- Date Revised 2021-07-02
Further Info :
Related Literature
English
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