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The Association between Adiponectin Single Nucleotide Polymorphisms and Side Effects of Isotretinoin in Acne Patients.

Author: Abu-SiniyehAhmed, Al-QarqazFiras, AlzoubiKarem H, GarbaMunir, KhabourOmar F

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Isotretinoin is a common treatment for moderate to severe acne. However, its effectiveness varies, and it can cause side effects like musculoskeletal pain, headache, and changes in lipid levels.
Paper Details　
Original Abstract of the Article :
Acne is a common condition of pilosebaceous follicle especially among young. Clinically, the most used medication in the treatment of moderate to severe acne is oral isotretinoin. However, interindividual variability in therapeutic response to isotretinoin and many side effects such as musculoskelet...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206862/

データ提供：米国国立医学図書館（NLM）

Adiponectin Polymorphisms and Isotretinoin Side Effects: Uncovering the Secrets of Acne Treatment

Acne, a common skin condition that often plagues young people, can feel like a prickly desert of frustration. This study explores the potential link between variations in the adiponectin gene and the side effects of isotretinoin, a commonly used acne medication. Researchers are like intrepid explorers, venturing into the genetic landscape to understand why some individuals experience different responses to treatment.

The Role of Genetics: Finding the Hidden Oasis of Treatment

This study examines the association between specific gene variations (polymorphisms) in the adiponectin gene and the occurrence of side effects from isotretinoin. It's like looking for a hidden oasis in the desert, a clue that might explain why some individuals experience different outcomes. The results suggest that genetic factors may play a role in how individuals respond to isotretinoin, offering potential insights into personalized treatment approaches.

Health Implications and Life Applications

This study adds to our understanding of the complex interplay between genetics and medication response. It highlights the potential for personalized medicine, where treatment decisions are tailored to an individual's genetic makeup. For individuals with acne, discussing their family history and potential genetic predispositions with their healthcare providers can help guide treatment decisions and potentially minimize side effects.

Dr.Camel's Conclusion

This research delves into the fascinating interplay between genetics and medication response. By understanding the genetic factors that influence how individuals react to acne treatments, we can pave the way for more personalized approaches, leading to better outcomes and fewer side effects. It's like finding the right oasis in the vast desert of acne treatments, ensuring the most beneficial journey for each individual.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-04-14
Further Info :

Pubmed ID

32411191

DOI: Digital Object Identifier

PMC7206862

Related Literature

Article Analysis
・Side Effects of isotretinoin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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