Paradoxical adverse drug reactions: descriptive analysis of French reports.

Author: BagheriHaleh, HakimiYan, MontastrucJean-Louis, PetitpainNadine, PinzaniVéronique

Paper Details 
Original Abstract of the Article :
Paradoxical adverse drug reactions (ADRs) are defined as being opposing reactions to the pharmacological effect of drugs in relation to its pharmacodynamic properties. Their diagnosis is difficult as they are relatively rare with atypical clinical presentation (with the possibility of being confused...See full text at original site
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引用元:
https://doi.org/10.1007/s00228-020-02892-2

データ提供:米国国立医学図書館(NLM)

Paradoxical ADRs: A Puzzling Phenomenon in the Desert of Pharmacology

In the vast desert of pharmacology, we encounter a wide range of drug reactions. Sometimes, these reactions are unexpected and even paradoxical, defying our understanding of how medications should work. This study explores the phenomenon of paradoxical adverse drug reactions (ADRs), a peculiar type of reaction that runs counter to the expected pharmacological effects.

The researchers conducted a descriptive analysis of paradoxical ADR reports in the French PharmacoVigilance Database. They found that these reactions are relatively rare and often misdiagnosed, potentially leading to under-reporting. The study highlights the challenges associated with identifying and managing paradoxical ADRs, urging clinicians to be vigilant in recognizing these atypical reactions.

Hidden Sands: The Challenges of Paradoxical ADRs

This study sheds light on the often-overlooked phenomenon of paradoxical ADRs. Their rarity and atypical presentation make them difficult to diagnose, emphasizing the need for heightened awareness among healthcare professionals.

Navigating the Complexities of Drug Reactions

Navigating the desert of drug reactions requires a keen eye for detail and a thorough understanding of the intricacies of medication interactions. This study serves as a reminder that even seemingly simple drugs can elicit complex and unexpected reactions.

Dr.Camel's Conclusion

This research underscores the importance of vigilant monitoring and reporting of adverse drug reactions, even those that seem paradoxical. By carefully observing and documenting drug reactions, we can better understand the complex interplay between medications and the human body, ensuring safer and more effective healthcare for all.

Date :
  1. Date Completed 2021-04-22
  2. Date Revised 2021-04-22
Further Info :

Pubmed ID

32418024

DOI: Digital Object Identifier

10.1007/s00228-020-02892-2

Related Literature

SNS
PICO Info
in preparation
Languages

English

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