Flexible liposomal gel dual-loaded with all-trans retinoic acid and betamethasone for enhanced therapeutic efficiency of psoriasis.

Author: DuYong-Zhong, HuangQiao-Ling, LuKong-Jun, QiJing, ShuGao-Feng, SunMin-Cheng, TanWei-Qiang, WangWei, XuXiao-Ling

Paper Details 
Original Abstract of the Article :
Psoriasis is a chronic immune-mediated inflammatory skin disease without effective treatment. The utilization of all trans-retinoic acid (TRA) and betamethasone (BT) for the treatment of psoriasis is still facing difficulties, due to their relatively poor stability, limited skin permeation, and syst...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245867/

データ提供:米国国立医学図書館(NLM)

A Novel Approach to Psoriasis Treatment: Flexible Liposomal Gel

The field of dermatology is always looking for better ways to treat psoriasis, a chronic inflammatory skin condition. This study focuses on a new treatment strategy using flexible liposomes to deliver two key drugs, all-trans retinoic acid (TRA) and betamethasone (BT), directly to the skin. This approach aims to improve the effectiveness of psoriasis treatment while minimizing side effects.

Flexible Liposomes: A Smart Delivery System

Flexible liposomes are like tiny, microscopic bubbles that can carry drugs deep into the skin. They're a bit like camels, able to carry a heavy load of drugs across the harsh terrain of the skin. This allows for targeted drug delivery, reducing the need for high doses and minimizing systemic side effects. This study found that flexible liposomes, loaded with both TRA and BT, showed significant promise in treating psoriasis.

Implications for Psoriasis Management

This research suggests that flexible liposomal gel could offer a more effective and safer way to treat psoriasis. As a dermatologist, I'm excited about the potential of this approach to improve the lives of patients living with psoriasis. The targeted delivery system could lead to better symptom control and a higher quality of life for patients.

Dr.Camel's Conclusion

This innovative research unveils the potential of flexible liposomes as a powerful tool in the fight against psoriasis. The targeted drug delivery system may revolutionize psoriasis treatment, offering patients more effective and safer therapies.

Date :
  1. Date Completed 2021-02-01
  2. Date Revised 2021-02-01
Further Info :

Pubmed ID

32448273

DOI: Digital Object Identifier

PMC7245867

Related Literature

SNS
PICO Info
in preparation
Languages

English

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