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Systemic adjuvant therapy for adult patients at high risk for recurrent melanoma: A systematic review.

Author: BaetzTara D, FletcherGlenn G, KnightGregory, McWhirterElaine, PetrellaTeresa M, RajagopalSudha, SongXinni

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This systematic review examines adjuvant therapies for cutaneous and mucosal melanoma, evaluating the effectiveness of immune checkpoint inhibitors and targeted therapies for high-risk patients.
Paper Details　
Original Abstract of the Article :
Cutaneous melanoma is typically treated with wide local excision and, when appropriate, a sentinel node biopsy. Many patients are cured with this approach but for patients who have cancers with high risk features there is a significant risk of local and distant relapse and death. Interferon-based ad...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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引用元：
https://doi.org/10.1016/j.ctrv.2020.102032

データ提供：米国国立医学図書館（NLM）

Adjuvant Therapy for Melanoma: New Hope for High-Risk Patients

The field of [oncology] is constantly striving to [improve treatment outcomes] for [patients with melanoma]. This systematic review explores [current approaches] to [systemic adjuvant therapy] for [adult patients at high risk of recurrent melanoma]. The authors analyze the [efficacy and safety] of [various adjuvant therapies] including [immune checkpoint inhibitors and targeted therapies].

Immune Checkpoint Inhibitors: A Promising Adjuvant Therapy

The review reveals that [immune checkpoint inhibitors] have shown [significant efficacy] in [adjuvant treatment of high-risk melanoma patients]. It highlights the [potential for these therapies] to [reduce the risk of recurrence] and [improve survival outcomes].

Personalized Treatment: Tailoring Care to Individual Needs

The research emphasizes the [importance of personalized treatment] for [melanoma patients] based on [their individual risk factors and disease characteristics]. It underscores the [need for ongoing research] to [further refine treatment strategies] and to [identify patients] who may [benefit most] from [specific therapies].

Dr.Camel's Conclusion

Imagine a desert landscape, where a resilient plant survives against all odds. Just as this plant adapts to its challenging environment, melanoma patients face a formidable battle. This systematic review explores new weapons in the fight against melanoma, highlighting the potential of immune checkpoint inhibitors to improve outcomes for high-risk patients. The journey toward a cure is ongoing, but with continued research and personalized approaches, we can strive for a future where melanoma is no longer a daunting adversary.
Date :
  1. Date Completed 2020-06-24
  2. Date Revised 2023-12-13
Further Info :

Pubmed ID

32473511

DOI: Digital Object Identifier

10.1016/j.ctrv.2020.102032

Related Literature

Article Analysis
・Effective treatment of melanoma
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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