Paper Details

  1. Home
  2. Paper Details

Non-metastatic castration-resistant prostate cancer: current status and future directions.

Author: BarataPedro C, GarciaJorge A, GuptaRuby, ShengIris Y

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Non-metastatic castration resistant prostate cancer (M0CRPC) is a challenging condition, where patients exhibit rising PSA levels but lack detectable metastases. This review summarizes the definition, diagnosis, treatment, and ongoing clinical trials for M0CRPC, highlighting the role of newer imaging modalities in detecting advanced prostate cancer. Novel oral androgen receptor inhibitors have shown positive impacts on metastasis-free and overall survival, making them suitable treatment options for M0CRPC.
Paper Details　
Original Abstract of the Article :
INTRODUCTION: The emergence of novel hormonal therapies and the increase availability of sensitive next-generation imaging techniques has significantly changed the management of recurrent prostate cancer. AREAS COVERED: In this review, we summarize the definition, diagnosis, treatment, and ongoing ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1080/14737140.2020.1772759

データ提供：米国国立医学図書館（NLM）

Non-Metastatic Castration-Resistant Prostate Cancer: Navigating a Shifting Landscape

Prostate cancer, a prevalent and often challenging disease, requires careful management and innovative treatment strategies. This review delves into the evolving landscape of non-metastatic castration-resistant prostate cancer (M0CRPC), exploring its definition, diagnosis, treatment, and ongoing research. It’s like charting a course through a shifting desert landscape, adapting to new discoveries and refining treatment approaches.

M0CRPC: A New Frontier in Prostate Cancer

This review highlights the complexities of M0CRPC, a stage of prostate cancer characterized by biochemical progression despite castration levels of testosterone. It emphasizes the importance of sensitive imaging techniques for early detection and the role of novel hormonal therapies in delaying disease progression. It’s like navigating a new oasis in the desert of prostate cancer research, exploring a different path to manage this challenging disease.

A New Perspective on Prostate Cancer Treatment

This review offers a comprehensive overview of M0CRPC, providing valuable insights for clinicians and patients seeking effective treatment options. It underscores the importance of early detection, personalized therapy, and ongoing research in this evolving field. Think of it as a compass guiding us through the intricate desert of prostate cancer, leading us to new treatments and better outcomes.

Dr. Camel's Conclusion

This review highlights the evolving landscape of M0CRPC, emphasizing the importance of early detection, advanced imaging techniques, and novel hormonal therapies. It’s a reminder that the desert of prostate cancer research is constantly shifting, offering new challenges and opportunities for innovation.
Date :
  1. Date Completed 2021-04-06
  2. Date Revised 2021-04-06
Further Info :

Pubmed ID

32508166

DOI: Digital Object Identifier

10.1080/14737140.2020.1772759

Related Literature

Article Analysis
・Side Effects of enzalutamide
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.