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Aromatase Inhibitors for the Treatment of Breast Cancer: A Journey from the Scratch.

Author: DubeyAmit, JainAkhlesh, MishraKeerti, RatrePooja, TharejaSuresh, VyasAmber

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Aromatase inhibitors are a type of medication that blocks the production of estrogen, which is a key driver of breast cancer growth. These medications are particularly effective in treating estrogen receptor-positive breast cancer in postmenopausal women. Third-generation aromatase inhibitors, like letrozole, anastrozole, and exemestane, are now standard treatments for postmenopausal breast cancer.
Paper Details　
Original Abstract of the Article :
Estrogens are essential for the growth of breast cancer in the case of premenopausal as well as in postmenopausal women. However, most of the breast cancer incidences are reported in postmenopausal women and the concurrent risk surges with an increase in age. Since the enzyme aromatase catalyses ess...See full text at original site
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引用元：
https://doi.org/10.2174/1871520620666200627204105

データ提供：米国国立医学図書館（NLM）

Aromatase Inhibitors: A Powerful Weapon in the Battle Against Breast Cancer

This review explores the role of aromatase inhibitors (AIs) in treating breast cancer, like exploring a hidden oasis of potent remedies in the desert of cancer treatment. AIs are specifically designed to target estrogen, a hormone that plays a crucial role in breast cancer development, particularly in postmenopausal women. The researchers delve into the mechanism of action of AIs and their effectiveness in treating estrogen receptor-positive (ER+) breast cancer.

Targeting Estrogen: A Precision Strike Against Breast Cancer

The study highlights the effectiveness of AIs in blocking estrogen production, thereby inhibiting the growth of ER+ breast cancer. It's like finding a rare and valuable resource in the desert, offering a powerful solution to a complex challenge. AIs have demonstrated their efficacy in treating breast cancer and have become an essential part of the therapeutic arsenal for this disease.

Hope for Breast Cancer Patients: A Oasis in the Desert

This review provides a glimpse into the promising future of breast cancer treatment, where targeted therapies are increasingly offering hope for patients. Like finding a life-sustaining oasis in a desolate desert, AIs are changing the landscape of breast cancer care, providing effective treatment options and improved outcomes for patients. This research reinforces the importance of continued research and development in the field of cancer treatment, offering a glimmer of hope in the fight against this debilitating disease.

Dr.Camel's Conclusion

Aromatase inhibitors are a significant breakthrough in the battle against breast cancer. They offer targeted and effective treatment options, providing a beacon of hope for patients. As we continue to explore and refine our understanding of cancer biology, we can expect to discover even more powerful tools and therapies, creating a brighter future for those affected by this devastating disease.

Date :
  1. Date Completed 2021-06-03
  2. Date Revised 2021-06-03
Further Info :

Pubmed ID

32593281

DOI: Digital Object Identifier

10.2174/1871520620666200627204105

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Languages

English

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