Efficacy and safety of risankizumab vs. secukinumab in patients with moderate-to-severe plaque psoriasis (IMMerge): results from a phase III, randomized, open-label, efficacy-assessor-blinded clinical trial.

Author: BeeckS, BlauveltA, GengZ, KellyM, PaulC, PoulinY, WarrenR B, WuT

Paper Details 
Original Abstract of the Article :
Patients with plaque psoriasis treated with biologic therapies need more efficacious, safe and convenient treatments to improve quality of life. Risankizumab and secukinumab inhibit interleukin-23 and interleukin-17A, respectively, and are effective in adult patients with moderate-to-severe plaque p...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983954/

データ提供:米国国立医学図書館(NLM)

Risankizumab vs. Secukinumab: A Head-to-Head Comparison in Plaque Psoriasis Treatment

This research delves into the realm of psoriasis treatment, comparing the efficacy and safety of two biologic therapies, risankizumab and secukinumab, in patients with moderate-to-severe plaque psoriasis. The researchers, like skilled clinicians navigating a vast desert of treatment options, sought to identify the most effective and convenient therapy for their patients. Their findings, like a treasure map guiding us through the complexities of psoriasis treatment, reveal valuable insights into the comparative effectiveness of these two biologic agents. The study demonstrated that both risankizumab and secukinumab effectively cleared psoriasis plaques, but risankizumab, with its less frequent dosing regimen, offered a more convenient treatment option.

A New Frontier in Psoriasis Treatment: Tailoring Therapy to Individual Needs

This research highlights the importance of tailoring psoriasis treatment to the individual needs of each patient. The study's findings, like a shimmering oasis in the desert of psoriasis treatment options, suggest that risankizumab, with its convenient dosing schedule, could be a valuable option for patients seeking a more manageable treatment regimen. This personalized approach could lead to improved treatment adherence and better outcomes for individuals with psoriasis.

Navigating the Landscape of Psoriasis Treatment: Finding the Right Path

This research underscores the need for a comprehensive understanding of the diverse treatment options available for psoriasis. By carefully considering the individual needs and preferences of each patient, healthcare professionals can guide them towards the most effective and convenient treatment path. This personalized approach can lead to better outcomes and improved quality of life for individuals living with psoriasis.

Dr. Camel's Conclusion

This research, like a camel caravan traversing the desert of psoriasis treatment options, sheds light on the comparative efficacy of risankizumab and secukinumab. The findings suggest that risankizumab, with its less frequent dosing regimen, offers a more convenient and potentially effective treatment option, highlighting the importance of personalized approaches to psoriasis management.
Date :
  1. Date Completed 2021-05-14
  2. Date Revised 2022-05-31
Further Info :

Pubmed ID

32594522

DOI: Digital Object Identifier

PMC7983954

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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