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Neratinib-Induced Duodenal Ulcer: A Case Report.
Author: DhakalAjay, FalksonCarla, GandhiShipra, KharelPrakash, MoftakharBahar, NiraulaSujan
Original Abstract of the Article :
We report a case of a 37-year-old woman who developed a duodenal ulcer while receiving adjuvant neratinib for HER2 positive breast cancer. The clinical course of abdominal pain was strongly correlated with the use of neratinib. An esophagogastroduodenoscopy (EGD) was performed and confirmed the diag...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315670/
データ提供:米国国立医学図書館(NLM)
Neratinib-Induced Duodenal Ulcer: A Case Study in the Desert of Drug Side Effects
The desert of medicine is full of unexpected encounters, and sometimes, medications can have unforeseen side effects. This case report describes a patient who developed a duodenal ulcer while receiving neratinib, a medication used for HER2-positive breast cancer.
The patient experienced abdominal pain that was strongly correlated with the use of neratinib. An esophagogastroduodenoscopy (EGD) confirmed the diagnosis of a large duodenal ulcer. The patient's symptoms resolved after stopping neratinib and receiving proton pump inhibitor treatment. This case highlights the importance of being aware of potential gastrointestinal side effects associated with neratinib, including the possibility of peptic ulcer disease.
Navigating the Unexpected Side Effects
This case report serves as a reminder that even medications with proven benefits can have unexpected side effects. It emphasizes the importance of vigilant monitoring and prompt intervention when adverse events occur.
The Shifting Sands of Drug Side Effects
This case underscores the need for a careful assessment of potential risks and benefits when prescribing medication, especially for individuals with pre-existing health conditions. We must constantly adapt our understanding of drug side effects as we navigate the ever-changing landscape of medical knowledge.
Dr.Camel's Conclusion
This case study is a reminder that the desert of medicine is full of hidden pathways and unexpected encounters. It emphasizes the importance of recognizing and managing drug side effects, even those that are rare or seemingly unrelated to the intended therapeutic effect.
Date :
- Date Completed n.d.
- Date Revised 2020-09-28
Further Info :
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English
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