Paper Details 
Original Abstract of the Article :
INTRODUCTION: Safinamide, a selective, reversible monoamine oxidase B inhibitor with a sodium channel inhibitory effect, improves symptoms in advanced Parkinson's disease (PD). This study aimed to confirm the long-term safety and efficacy of safinamide in Japanese PD patients with wearing-off. METH...See full text at original site
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引用元:
https://doi.org/10.1016/j.jns.2020.117012

データ提供:米国国立医学図書館(NLM)

Safinamide: A Beacon of Hope for Parkinson's Patients

Navigating the complexities of Parkinson's disease (PD) is like traversing a vast, unforgiving desert. This study, like a caravan seeking a source of water, explores the long-term safety and efficacy of safinamide in treating PD. The researchers embarked on a long-term, open-label study, a journey through time, to assess the effectiveness of safinamide in Japanese patients. Their findings, like a shimmering oasis, reveal encouraging results.

Safinamide's Impact on Parkinson's

The study demonstrates that safinamide, like a resourceful camel carrying vital supplies, can effectively improve the ON-time in PD patients without troublesome dyskinesias. The researchers found that safinamide, when added to levodopa treatment, significantly increased the ON-time by an average of 1.42 hours per day after 52 weeks. These findings, like a well-stocked oasis, offer hope for a better quality of life for PD patients.

Safinamide's Significance

Safinamide, like a trusty guide in the desert, has been shown to be safe and well-tolerated. This research offers valuable insights for healthcare professionals seeking to alleviate the symptoms of PD. The study highlights the importance of personalized medicine in treating PD, tailoring treatments to individual patient needs.

Dr.Camel's Conclusion

This study is a ray of hope in the desert of PD. Safinamide, like a reliable camel, shows promise in improving the lives of patients. While more research is needed, this study provides valuable insights into potential treatments for this debilitating disease.

Date :
  1. Date Completed 2021-05-14
  2. Date Revised 2021-05-14
Further Info :

Pubmed ID

32673884

DOI: Digital Object Identifier

10.1016/j.jns.2020.117012

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