Paper Details

  1. Home
  2. Paper Details

Voxelotor: A Novel Treatment for Sickle Cell Disease.

Author: HerityLeah B, LoweDenise Kozella, RodriguezLindsey Ritenour, VaughanDaleMarie M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Voxelotor, a novel agent targeting the pathophysiology of sickle cell disease (SCD), was found to be safe and effective as monotherapy or in combination with hydroxyurea. It may be considered for patients with SCD who have continued anemia and hemolysis despite being on maximum tolerated dose of hydroxyurea or in those who are hydroxyurea intolerant.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To review the pharmacological characteristics, clinical evidence, and place in therapy of voxelotor for the treatment of sickle cell disease (SCD). DATA SOURCES: A comprehensive literature search of PubMed (1966 to April 2020) was conducted. Key search terms included STUDY SELECTION AN...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1177/1060028020943059

データ提供：米国国立医学図書館（NLM）

Voxelotor: A Novel Treatment for Sickle Cell Disease

This research explores the [Pharmacological Treatment] of sickle cell disease (SCD). The study investigates the characteristics, clinical evidence, and therapeutic potential of voxelotor, a novel drug targeting the underlying pathophysiology of SCD. The findings suggest that voxelotor may be a safe and effective treatment for patients with SCD, offering a new therapeutic option for managing this complex and debilitating condition.

Voxelotor: A Promising Treatment for Sickle Cell Disease

This study highlights the potential of voxelotor as a novel treatment for SCD. The research demonstrates the drug's ability to increase hemoglobin levels and reduce hemolysis, potentially improving the quality of life for patients with SCD.

Hope for Sickle Cell Disease Patients

Just like a camel needs to find water in a desert, individuals with sickle cell disease require effective treatments to manage their condition. This research offers hope for patients with SCD, highlighting the potential of voxelotor as a promising new therapeutic option that can alleviate their symptoms and improve their well-being.

Dr. Camel's Conclusion

This study underscores the potential of voxelotor as a safe and effective treatment for sickle cell disease. The research highlights the drug's ability to improve hemoglobin levels and reduce hemolysis, offering hope for a better future for individuals living with this challenging condition.

Date :
  1. Date Completed 2021-02-24
  2. Date Revised 2021-02-24
Further Info :

Pubmed ID

32674605

DOI: Digital Object Identifier

10.1177/1060028020943059

Related Literature

Article Analysis
・Effects of voxelotor
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.