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Effects of roflumilast on arterial stiffness in COPD (ELASTIC): A randomized trial.
Author: BurghuberOtto C, FunkGeorg-Christian, GleissAndreas, HartlSylvia, KreibichNicole, UrbanMatthias H
Original Abstract of the Article :
Cardiovascular risk is substantially increased in patients with COPD and can be quantified via arterial stiffness. The PDE-IV inhibitor roflumilast revealed a potential reduction of COPD-related cardiovascular risk. We aimed to investigate the effects of roflumilast on arterial stiffness by quantifi...See full text at original site
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引用元:
https://doi.org/10.1111/resp.13914
データ提供:米国国立医学図書館(NLM)
Roflumilast and Arterial Stiffness: A Potential Benefit for COPD Patients
Chronic obstructive pulmonary disease (COPD) is a respiratory illness that increases the risk of cardiovascular disease. This study examines the effects of roflumilast, a phosphodiesterase-4 (PDE-IV) inhibitor, on arterial stiffness in patients with stable COPD. The research involved a randomized trial comparing arterial stiffness measurements in COPD patients receiving either roflumilast or placebo. The authors found that roflumilast treatment resulted in a significant reduction in arterial stiffness, suggesting a potential benefit for cardiovascular health in COPD patients.
A Glimpse into the Desert of COPD: Roflumilast and Arterial Stiffness
This study's findings offer a promising avenue for improving cardiovascular health in COPD patients. The significant reduction in arterial stiffness observed with roflumilast treatment highlights its potential to reduce cardiovascular risk in this population. This research underscores the importance of addressing the cardiovascular complications of COPD through effective pharmacological interventions.
Navigating the Desert of COPD: Seeking Strategies to Improve Cardiovascular Health
Imagine a vast desert where the only source of water is a distant oasis. This is the analogy for COPD patients, who face a challenging respiratory condition that can increase their risk of cardiovascular disease. This study offers hope by demonstrating the potential of roflumilast to improve cardiovascular health in COPD patients. The research highlights the importance of exploring new pathways to prevent and manage the cardiovascular complications associated with this chronic illness.
Dr. Camel's Conclusion
This study is like a wellspring of hope in the desert of COPD. It highlights the potential of roflumilast to improve cardiovascular health in patients with this challenging condition. As researchers, we must continue to explore new avenues and develop effective strategies to combat the multifaceted health challenges associated with COPD.
Date :
- Date Completed 2021-06-24
- Date Revised 2021-06-24
Further Info :
Related Literature
English
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