Oral 5-aminosalicylic acid for induction of remission in ulcerative colitis.

Author: FeaganBrian G, MacDonaldJohn K, MurrayAlistair, NguyenTran M, ParkerClaire E

Paper Details 
Original Abstract of the Article :
Oral 5-aminosalicylic acid (5-ASA) preparations were intended to avoid the adverse effects of sulfasalazine (SASP) while maintaining its therapeutic benefits. It was previously found that 5-ASA drugs in doses of at least 2 g/day were more effective than placebo but no more effective than SASP for in...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8189994/

データ提供:米国国立医学図書館(NLM)

Oral 5-Aminosalicylic Acid: A Promising Treatment for Ulcerative Colitis

Ulcerative colitis (UC) is a chronic inflammatory bowel disease that affects the colon. This research reviews the use of oral 5-aminosalicylic acid (5-ASA) preparations in inducing remission in UC patients. The study compares the efficacy of 5-ASA to placebo and sulfasalazine, a related drug. The review concludes that 5-ASA doses of at least 2 g/day are more effective than placebo but not more effective than sulfasalazine in inducing remission in UC.

5-ASA: A Valuable Option for UC Management

This review highlights the therapeutic potential of oral 5-ASA in managing ulcerative colitis. While 5-ASA may not be superior to sulfasalazine, it offers a valuable alternative for patients who experience side effects from sulfasalazine. The review underscores the importance of adequate 5-ASA dosage for achieving optimal therapeutic effects.

Living with UC: Finding the Right Treatment

Ulcerative colitis can have a significant impact on quality of life. This review provides valuable insights into the use of 5-ASA as a potential treatment option. It emphasizes the importance of working closely with your doctor to find the most effective treatment approach for your individual needs and to manage the symptoms of UC effectively.

Dr.Camel's Conclusion

Just as a camel adapts to its harsh desert environment, UC patients must learn to navigate the challenges of this chronic condition. This review provides valuable information about 5-ASA, a potential weapon in the fight against UC. By understanding the various treatment options available, patients can partner with their doctors to create a personalized plan for managing their condition and improving their quality of life.

Date :
  1. Date Completed 2020-10-09
  2. Date Revised 2022-09-16
Further Info :

Pubmed ID

32786164

DOI: Digital Object Identifier

PMC8189994

Related Literature

Article Analysis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.