Life-threatening disseminated enterovirus infection during combined rituximab and ibrutinib maintenance treatment for mantle cell lymphoma: a case report.

Author: CanaDenis, HessGeorg, HigerMaximilian, PodlechJuergen, Schadmand-FischerSimin, SchwartingAndreas, TeschnerDaniel, TheobaldMatthias, WölfelThomas

Paper Details 
Original Abstract of the Article :
Rituximab is a well-established component of treatment regimens for B-cell non-Hodgkin lymphoma. Rituximab binds the CD20 antigen on the surface of B lymphocytes, causing an enhanced clearance of malignant and benign B cells. Thus, rituximab leads to depletion of normal B lymphocytes as well, which ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456041/

データ提供:米国国立医学図書館(NLM)

A Case of Life-Threatening Enterovirus Infection: When Immune Suppression Meets Viral Invasion

The immune system is like a protective oasis in the desert of our bodies, shielding us from harmful invaders. However, when this oasis is compromised, we become vulnerable to infection. This study explores the complex interplay between immune suppression and viral infection, highlighting a case of life-threatening disseminated enterovirus infection in a patient undergoing combined rituximab and ibrutinib treatment for mantle cell lymphoma. These drugs, while effective in treating lymphoma, can significantly suppress the immune system, leaving the patient susceptible to opportunistic infections.

Navigating the Desert of Immune Suppression

This case study serves as a reminder that immune suppression, while a necessary part of some cancer treatments, can have serious consequences. Close monitoring and prompt intervention are crucial for managing the risks associated with immune suppression and preventing potentially life-threatening infections.

The Importance of Vigilance and Early Intervention

This case highlights the importance of vigilance and early intervention in patients undergoing immune-suppressive therapies. Regular monitoring for signs of infection and prompt treatment are vital for ensuring patient safety and minimizing the risks associated with immune suppression.

Dr. Camel's Conclusion

This case study underscores the delicate balance between fighting cancer and protecting the immune system. It reminds us that while immune suppression can be a powerful tool in cancer treatment, it's crucial to remain vigilant and address potential complications promptly. This case serves as a valuable lesson in navigating the desert of immune suppression, emphasizing the importance of careful monitoring and early intervention.

Date :
  1. Date Completed 2021-05-14
  2. Date Revised 2021-05-14
Further Info :

Pubmed ID

32859260

DOI: Digital Object Identifier

PMC7456041

Related Literature

SNS
PICO Info
in preparation
Languages

English

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