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Continuous intravenous infusions of famotidine maintain high intragastric pH in duodenal ulcer.

Author: KaufmanD, KempfM, MerkiH S, NeumannJ, RöhmelJ, WaltR P, WitzelL

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Primed infusions of famotidine were effective in raising intragastric pH over 24 hours in duodenal ulcer patients. Both 3.2 mg/h and 4 mg/h doses were effective but famotidine was less effective during the day when meals were taken.
Paper Details　
Original Abstract of the Article :
Three double blind crossover studies were carried out to assess the ability of primed infusions of famotidine to raise intragastric pH over 24 hours in 12 duodenal ulcer patients. pH was measured continuously using intragastric electrodes and solid state recording devices. The studies compared the e...See full text at original site
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引用元：
https://doi.org/10.1136/gut.29.4.453

データ提供：米国国立医学図書館（NLM）
in preparation
Date :
  1. Date Completed 1988-07-13
  2. Date Revised 2019-05-01
Further Info :

Pubmed ID

3286384

DOI: Digital Object Identifier

10.1136/gut.29.4.453

Related Literature

Article Analysis
・Effects of famotidine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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