Hepatotoxicity associated with choline magnesium trisalicylate: case report and review of salicylate-induced hepatotoxicity.

Author: CersosimoR J, MatthewsS J

Paper Details 
Original Abstract of the Article :
A case of a 21-year-old woman who had developed mild hepatotoxicity while receiving choline magnesium trisalicylate therapy is described. She presented with fever and mild hepatic enzyme elevations before salicylate therapy was instituted. Liver function tests (LFT) returned to normal within five da...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1177/1060028087021007-810

データ提供:米国国立医学図書館(NLM)

Hepatotoxicity Associated with Choline Magnesium Trisalicylate

Hepatotoxicity, or liver damage, is a critical concern in the field of medicine. This research investigates a case report of a 21-year-old woman who experienced mild hepatotoxicity while taking choline magnesium trisalicylate, a common medication. The study utilized a case report approach to analyze the individual's experience, and a review of the literature to gather existing knowledge on salicylate-induced hepatotoxicity. The authors identified a link between choline magnesium trisalicylate and the development of liver enzyme elevations in this patient. The findings highlight the importance of monitoring liver function during salicylate therapy, as it can have unexpected consequences.

Salicylate Therapy and Liver Function

The patient in this case report presented with fever and elevated liver enzymes before initiating salicylate therapy. Although her liver function tests returned to normal after hospitalization, she continued to experience daily fevers. After choline magnesium trisalicylate was administered, her liver function tests began to rise again. The authors concluded that this rise in liver enzymes was likely due to salicylate hepatotoxicity, as the LFT values quickly returned to normal after the medication was discontinued. This emphasizes the need for careful monitoring of patients on salicylate medications, particularly those with pre-existing liver conditions.

Liver Health and Salicylate Medications

This research underscores the importance of understanding the potential risks associated with salicylate medications, especially regarding liver health. While salicylates can be effective for treating various conditions, they can also cause liver damage, especially when used for prolonged periods. This research provides valuable insight for doctors and patients to make informed decisions about the use of salicylates, considering the potential risks and benefits.

Dr. Camel's Conclusion

Just like a camel carefully navigates the harsh desert landscape, doctors need to cautiously tread the path of medication administration, always considering the potential risks and benefits for their patients. This study serves as a reminder that even seemingly benign medications can have unexpected consequences. By carefully monitoring liver function and being vigilant for potential complications, doctors can help ensure that patients receive the best possible care.

Date :
  1. Date Completed 1987-09-21
  2. Date Revised 2019-09-12
Further Info :

Pubmed ID

3301251

DOI: Digital Object Identifier

10.1177/1060028087021007-810

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.