Efficacy and safety of solriamfetol for excessive daytime sleepiness in narcolepsy and obstructive sleep apnea: a systematic review and meta-analysis of clinical trials.

Author: JhaDivyanshu, K CBibek, RayBarun Kumar, SinghRajshree, SubediRoshan, ThakurRahul Kumar

Paper Details 
Original Abstract of the Article :
Excessive daytime sleepiness (EDS) is the inability to maintain wakefulness and alertness during the major waking episodes of the day, with sleep occurring unintentionally or at inappropriate times. Solriamfetol is a selective norepinephrine-dopamine reuptake inhibitor approved for EDS. This review ...See full text at original site
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引用元:
https://doi.org/10.1016/j.sleep.2020.09.019

データ提供:米国国立医学図書館(NLM)

Solriamfetol: A New Path for Managing Excessive Daytime Sleepiness

This research provides a comprehensive review of solriamfetol, a medication used to treat excessive daytime sleepiness (EDS), a common symptom of narcolepsy and obstructive sleep apnea. The study analyzed data from multiple clinical trials to assess the efficacy and safety of solriamfetol in managing EDS in these conditions.

Fighting Fatigue: A Systematic Review of Solriamfetol

The meta-analysis of solriamfetol's effects on EDS revealed that it significantly improves wakefulness and alertness in patients with narcolepsy and OSA. The study also concluded that solriamfetol is generally well-tolerated, with a manageable side effect profile. These findings suggest that solriamfetol could be a valuable treatment option for managing EDS in these conditions.

The Desert of Sleepiness: Finding a Balance

This study provides a valuable overview of solriamfetol's potential to improve the lives of individuals suffering from EDS. The drug's ability to improve wakefulness and alertness can have a significant impact on quality of life, allowing individuals to participate more fully in daily activities and social interactions. However, it is important to remember that EDS is a complex symptom, and treatment should be individualized, taking into account the specific underlying condition and potential side effects of the medication.

Dr.Camel's Conclusion

This research presents a compelling case for solriamfetol as a promising treatment for EDS. The study's findings provide valuable insights into the drug's efficacy, safety, and potential role in improving the lives of individuals struggling with EDS. This research is a reminder that the quest for solutions to sleep-related disorders continues, and the discovery of new and effective treatments offers hope for a better future for those affected.
Date :
  1. Date Completed 2021-06-21
  2. Date Revised 2021-06-21
Further Info :

Pubmed ID

33032062

DOI: Digital Object Identifier

10.1016/j.sleep.2020.09.019

Related Literature

SNS
PICO Info
in preparation
Languages

English

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