Glucose tolerance in hypertensive patients during treatment with the calcium antagonist, felodipine.

Author: ElmfeldtD, HednerT, SjögrenE, SmithU, Von SchenckH

Paper Details 
Original Abstract of the Article :
1 Twelve non-diabetic hypertensive male patients insufficiently controlled by a diuretic were included in a double-blind, randomised study. In addition placebo or felodipine was given for 4 weeks followed by a 2 week wash-out period, after which the alternative treatment was given for another 4 week...See full text at original site
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引用元:
https://doi.org/10.1111/j.1365-2125.1987.tb03155.x

データ提供:米国国立医学図書館(NLM)

Felodipine: A Calcium Antagonist for Hypertension, But What About Glucose Tolerance?

Hypertension, also known as high blood pressure, is a common health issue, and the search for effective and safe treatments is ongoing. This study investigates the effects of felodipine, a calcium antagonist, on glucose tolerance in hypertensive patients. The researchers conducted a double-blind, randomized study, comparing felodipine with placebo, to examine its impact on blood pressure, plasma noradrenaline levels, and glucose tolerance. It's like examining the impact of a desert oasis on a traveler's journey, observing how the oasis influences both their physical and metabolic well-being.

A Balance Act: Managing Blood Pressure While Preserving Glucose Tolerance

The study demonstrates that felodipine effectively reduces blood pressure without significantly affecting glucose tolerance. This is a crucial finding, as it suggests that felodipine may be a safe and effective treatment option for hypertensive patients who are also at risk for diabetes. The researchers also observed an increase in plasma noradrenaline levels, which could be a potential side effect to consider.

Navigating the Desert of Health: Finding the Right Balance

This study highlights the importance of carefully monitoring glucose tolerance in patients undergoing treatment for hypertension. It's a reminder that the desert of health is complex, with interconnected pathways and potential side effects.

Dr.Camel's Conclusion

This research provides valuable insights into the safety and efficacy of felodipine for hypertensive patients, suggesting that it may be a suitable option for those at risk for diabetes. It's like finding a safe oasis in a vast desert, providing relief and nourishment without compromising overall health.

Date :
  1. Date Completed 1987-10-16
  2. Date Revised 2019-05-10
Further Info :

Pubmed ID

3304386

DOI: Digital Object Identifier

10.1111/j.1365-2125.1987.tb03155.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

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