Capsule-related dysphagia and the use of netupitant/palonosetron (Akynzeo™) capsules - A report of two cases and a solution.

Author: BehbahanyKevin, BubaloJoseph

Paper Details 
Original Abstract of the Article :
Netupitant/palonestron (NEPA, Akynzeo™) is a fixed combination of netupitant 300 mg and palonosetron 0.5 mg that is indicated for the prevention of chemotherapy-induced nausea and vomiting (CINV). NEPA is supplied as a hard gelatin capsule and indicated to be administered whole with or without food....See full text at original site
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引用元:
https://doi.org/10.1177/1078155220965671

データ提供:米国国立医学図書館(NLM)

Navigating Capsule-related Dysphagia with Netupitant/Palonosetron (Akynzeo™)

Netupitant/palonosetron (NEPA), a fixed combination medication used to prevent chemotherapy-induced nausea and vomiting (CINV), comes in a hard gelatin capsule form. This [case report] highlights two patient cases where difficulty swallowing the capsule (dysphagia) led to the administration of the medication's components in separate formulations. The authors discuss the potential for maintaining efficacy when administering NEPA in this alternative manner.

Maintaining Efficacy: A Solution for Dysphagia

In the cases presented, the patients experienced difficulty swallowing the NEPA capsule, leading to the separation of the medication's components. Despite this modification, the authors observed that [efficacy was maintained], suggesting that the alternative administration method could be a viable option for patients experiencing dysphagia. The study also highlights the importance of [flexibility and adaptability] in clinical practice, adapting treatment strategies to meet individual patient needs.

Optimizing Medication Administration for Patients with Dysphagia

This case report underscores the importance of considering individual patient needs when administering medications. For patients experiencing dysphagia, alternative administration methods, such as separating components, can be explored to ensure optimal medication delivery and maintain therapeutic efficacy. This approach emphasizes the need for open communication and collaboration between patients and clinicians in optimizing medication management.

Dr. Camel's Conclusion

This case report is like a reminder that in the desert of medication management, there are often multiple paths to achieve the desired outcome. When faced with challenges like dysphagia, flexibility and creativity can lead to solutions that ensure optimal patient care. This research emphasizes the importance of individualized treatment approaches and continuous learning in the field of medication administration.
Date :
  1. Date Completed 2021-07-05
  2. Date Revised 2021-07-05
Further Info :

Pubmed ID

33100182

DOI: Digital Object Identifier

10.1177/1078155220965671

Related Literature

SNS
PICO Info
in preparation
Languages

English

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