[Comparative clinical study of nalbuphine and fentanyl. Effects and side effects with special reference to the induction phase].

Author: BrandtL, DudaD, MüllerH

Paper Details 
Original Abstract of the Article :
In a previous study concerning balanced anesthesia we realized that the adrenergic sympathetic reaction caused by intubation could not be suppressed by nalbuphine-HCl (NAL), a new narcotic agonist-antagonist in the same way as by fentanyl (FE). The aim of the study was to investigate whether the obs...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/3310727

データ提供:米国国立医学図書館(NLM)

Nalbuphine vs. Fentanyl for Anesthesia Induction

Anesthesia induction is a crucial phase of surgery, and the choice of medications can impact patient outcomes. This study compared the effects and side effects of nalbuphine and fentanyl, two commonly used opioid analgesics, during anesthesia induction. The researchers conducted a randomized trial involving two groups of surgical patients, investigating the hemodynamic and autonomic responses to these drugs.

Nalbuphine vs. Fentanyl: Different Responses

The study's findings, like a detailed map of a desert landscape, reveal distinct hemodynamic and autonomic responses to nalbuphine and fentanyl during anesthesia induction. Nalbuphine, a mixed agonist-antagonist opioid, caused a more pronounced adrenergic sympathetic reaction compared to fentanyl, a pure opioid agonist. This difference, like a subtle shift in desert winds, might have implications for managing patient responses during anesthesia induction.

Choosing the Right Opioid

The research underscores the importance of carefully selecting the right opioid for anesthesia induction based on individual patient needs and potential risks. Like a desert traveler choosing the right path based on terrain and weather conditions, choosing the right opioid can optimize patient safety and comfort during anesthesia induction. Consult with a healthcare professional to discuss the best opioid choice for your specific needs and circumstances.

Dr. Camel's Conclusion

This research, like a camel caravan carefully navigating a complex desert route, provides valuable insights into the nuances of opioid use during anesthesia induction. The study's findings, like a desert oasis offering different types of refreshments, highlight the importance of considering the unique characteristics of each opioid to optimize patient outcomes. Remember, like a camel caravan adapting to the changing desert landscape, patient care requires a flexible and tailored approach to ensure optimal safety and well-being.

Date :
  1. Date Completed 1987-11-13
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

3310727

DOI: Digital Object Identifier

3310727

Related Literature

SNS
PICO Info
in preparation
Languages

German

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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