Panuveitis in patient on ipilimumab/nivolumab combination for small-cell lung cancer treated with an intravitreal dexamethasone implant.

Author: BernickerEric H, C ScheflerAmy, El RahiCynthia, L HeflerJade, M BaileyLauren

Paper Details 
Original Abstract of the Article :
Label="BACKGROUND" NlmCategory="BACKGROUND">Immunotherapy with checkpoint inhibitors has demonstrated durable responses and remarkable antitumor effects in a variety of cancers. Although these agents are generally well-tolerated, patients can experience immune-related adverse events (irAEs) that req...See full text at original site
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引用元:
https://doi.org/10.1177/1078155220969792

データ提供:米国国立医学図書館(NLM)

Panuveitis in a Lung Cancer Patient: An Unexpected Oasis in the Desert of Immunotherapy

This case report describes a rare case of panuveitis, an inflammatory eye condition, in a patient receiving immunotherapy with checkpoint inhibitors for small-cell lung cancer. The report highlights the importance of recognizing and managing potential immune-related adverse events associated with immunotherapy.

Immune-Related Ocular Toxicity: Navigating the Desert of Unexpected Reactions

The case highlights the potential for immune-related ocular toxicities, even in rare cases, during immunotherapy. The patient's panuveitis was successfully managed with an intravitreal dexamethasone implant, demonstrating the effectiveness of prompt intervention. It's a reminder that the desert of immunotherapy, while offering promising treatments, can sometimes present unexpected challenges, requiring vigilance and effective management strategies.

Immunotherapy: A New Frontier in Cancer Treatment

This case report underscores the importance of continued research and vigilance in the use of immunotherapy, ensuring patient safety and effective management of potential adverse events. While immunotherapy offers tremendous potential for cancer treatment, it's crucial to recognize that the desert of cancer treatment can present uncharted territories, requiring constant exploration and adaptation.

Dr.Camel's Conclusion

This case report offers a valuable lesson in the world of immunotherapy. While this treatment holds tremendous promise for cancer patients, it's essential to be aware of potential immune-related adverse events, such as panuveitis. By recognizing and managing these challenges, we can continue to explore the vast desert of immunotherapy, ensuring its safe and effective use for patients.

Date :
  1. Date Completed 2021-07-05
  2. Date Revised 2021-07-05
Further Info :

Pubmed ID

33108990

DOI: Digital Object Identifier

10.1177/1078155220969792

Related Literature

SNS
PICO Info
in preparation
Languages

English

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