Brugada Phenocopy: A Case of Incessant Ventricular Tachycardia in a Patient with Tricyclic Antidepressant Overdose.

Brugada Phenocopy: A Case of Incessant Ventricular Tachycardia

This case report investigates a rare occurrence of Brugada phenocopy (BrP) in a patient who experienced incessant ventricular tachycardia (VT) after a tricyclic antidepressant overdose. BrP is an electrocardiogram (ECG) pattern that can be mistaken for Brugada syndrome, a genetic condition that increases the risk of sudden cardiac death. The researchers aimed to highlight the potential for BrP to occur in individuals with tricyclic antidepressant overdose, even if they don't have Brugada syndrome.

The case report describes a 34-year-old woman who presented to the emergency department with VT cardiac arrest following a nortriptyline overdose. Her ECG revealed a pattern suggestive of BrP, but further investigation confirmed that the BrP was induced by nortriptyline intoxication. The BrP resolved after treatment with intravenous sodium bicarbonate, and the patient made a full recovery. This case highlights the importance of considering drug intoxication as a potential cause of BrP, even in individuals without a known history of Brugada syndrome.

Tricyclic Antidepressants: Potential for Cardiac Complications

This case report emphasizes the potential for tricyclic antidepressants to induce cardiac complications, such as BrP. It's crucial for healthcare providers to be aware of this potential risk and to carefully monitor patients taking these medications. Patients should be informed of the potential side effects of their medications and encouraged to report any unusual symptoms or changes in their health.

Navigating Medication Safety: A Collaborative Journey

This case report underscores the importance of a collaborative approach to medication safety. Patients, healthcare providers, and pharmacists must work together to ensure that medications are used safely and effectively. Open communication, careful monitoring, and a proactive approach to addressing potential risks are crucial for preventing serious adverse events and ensuring patient well-being.

Dr. Camel's Conclusion

This case report reminds us that even seemingly benign medications can have unexpected and potentially serious side effects. Just as the desert can conceal hidden dangers, the human body can react in complex and unpredictable ways to medication. By working together, patients and healthcare professionals can navigate the complex world of medication safety and ensure the best possible outcomes for everyone.