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Fatal Heart Failure Induced by Pazopanib in a Sarcoma Patient Previously Treated with Gemcitabine.
Author: BadalamentiGiuseppe, Di LisiDaniela, FilorizzoClarissa, GuarinoTommaso, LunettaMonica, MannoGirolamo, NovoGiuseppina, RussoAntonio, SantanelliGiulia
Original Abstract of the Article :
Gemcitabine is commonly used for various solid organ malignancies with rarely reported cardiac side effects such as cardiomyopathy. Pazopanib usually can cause arterial hypertension but cases of heart failure have recently been reported. We describe a case of fatal heart failure after treatment with...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7640551/
データ提供:米国国立医学図書館(NLM)
Pazopanib: A Potential Cardiac Risk in Sarcoma Patients?
Cancer treatment often involves the use of chemotherapy drugs that can have significant side effects, including cardiotoxicity. This case report highlights a fatal case of heart failure in a 55-year-old female with sarcoma who received treatment with gemcitabine and pazopanib. The authors describe the patient's clinical course, emphasizing the potential cardiotoxicity of these drugs.
The authors highlight the importance of considering the potential cardiotoxicity of pazopanib, particularly in patients who have previously received other cardiotoxic drugs, such as gemcitabine. They emphasize the need for careful monitoring of cardiac function in patients receiving these drugs and the importance of early detection and management of cardiac complications.
A Cautionary Tale: Recognizing Potential Cardiac Risks in Cancer Treatment
This case report serves as a cautionary tale, underscoring the importance of recognizing potential cardiac risks associated with cancer treatment. The authors highlight the need for careful monitoring of cardiac function in patients receiving cardiotoxic drugs and the importance of early detection and management of cardiac complications. This case emphasizes the need for a multidisciplinary approach to patient care, involving both oncologists and cardiologists to optimize treatment outcomes.
Navigating the Complexities of Cancer Treatment
Cancer treatment is often complex and can involve significant side effects. This case report highlights the importance of considering the potential cardiotoxicity of chemotherapy drugs, particularly in patients with pre-existing cardiac conditions or those who have previously received other cardiotoxic agents. Healthcare professionals must be vigilant in monitoring cardiac function and managing cardiac complications to ensure optimal patient outcomes.
Dr.Camel's Conclusion
This case report serves as a cautionary reminder of the potential cardiotoxicity of chemotherapy drugs, particularly pazopanib, in patients with sarcoma. The authors emphasize the need for careful monitoring of cardiac function in patients receiving these drugs and the importance of early detection and management of cardiac complications. This case highlights the need for a multidisciplinary approach to cancer care, involving both oncologists and cardiologists to optimize treatment outcomes. Just as the camel navigates the harsh desert environment, we must approach cancer treatment with a mindful awareness of potential risks and a commitment to providing optimal patient care.
Date :
- Date Completed n.d.
- Date Revised 2020-11-07
Further Info :
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