Upfront triple oral combination therapy including selexipag in a high-risk patient with idiopathic pulmonary arterial hypertension: a case report.

Author: GiulianiLivio, PierdomenicoSante Donato, PietrangeloCarla, RossiSerena

Paper Details 
Original Abstract of the Article :
BACKGROUND: Selexipag is an oral selective prostacyclin IP receptor agonist approved in patients with low- and intermediate-risk pulmonary hypertension (PH); evidence in patients at high risk is lacking. CASE SUMMARY: A 42-year-old woman with worsening dyspnoea (World Health Organization functional...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649462/

データ提供:米国国立医学図書館(NLM)

Triple Oral Combination Therapy: A Promising Oasis in the Desert of Pulmonary Arterial Hypertension (PAH)

This case report delves into the complex realm of pulmonary arterial hypertension (PAH), a debilitating disease characterized by high blood pressure in the pulmonary arteries. The study presents a case of a high-risk PAH patient who responded favorably to an off-label triple oral combination therapy, including selexipag, a selective prostacyclin IP receptor agonist.

Navigating the Sandstorms of PAH with Triple Therapy

This case report offers a glimpse into the potential of triple oral combination therapy, including selexipag, for managing high-risk PAH patients. The patient's significant clinical and hemodynamic improvement suggests that this approach may offer a valuable alternative to traditional parenteral therapies, particularly for patients who struggle with adherence to intravenous treatments.

Embracing New Therapeutic Strategies

This case report highlights the importance of exploring new therapeutic strategies for managing PAH. The successful outcome of this triple oral combination therapy encourages further investigation of this approach, potentially paving the way for improved treatment options for patients with this challenging disease.

Dr. Camel's Conclusion

The desert of PAH is vast and unforgiving, but this case report offers a promising oasis, suggesting the potential of triple oral combination therapy as a valuable tool for managing this debilitating disease. While further research is needed to confirm its efficacy, this case report provides a beacon of hope for patients navigating the challenges of PAH.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-04-18
Further Info :

Pubmed ID

33204960

DOI: Digital Object Identifier

PMC7649462

Related Literature

SNS
PICO Info
in preparation
Languages

English

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