Association between anticholinergic burden and anticholinergic adverse outcomes in the elderly: Pharmacological basis of their predictive value for adverse outcomes.

Author: CabralAna C, Castel-BrancoM Margarida, Fernandez-LlimosFernando, FigueiredoIsabel V, LavradorMarta, VeríssimoManuel T

Paper Details 
Original Abstract of the Article :
The use of anticholinergic drugs and other drugs with anticholinergic activity is highly prevalent in older people. Cumulative anticholinergic effects, known as anticholinergic burden, are associated with important peripheral and central adverse effects and outcomes. Several methods have been develo...See full text at original site
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引用元:
https://doi.org/10.1016/j.phrs.2020.105306

データ提供:米国国立医学図書館(NLM)

Anticholinergic Burden and Its Impact on the Elderly

The field of geriatric medicine is dedicated to understanding the unique health needs of older adults. This review focuses on the use of anticholinergic drugs and the concept of anticholinergic burden, which refers to the cumulative anticholinergic effects of medications. The authors examine the prevalence of anticholinergic drug use in older adults and its potential association with adverse effects, including peripheral and central nervous system complications. The review explores different methods for quantifying anticholinergic burden and their predictive value for adverse outcomes, highlighting the importance of using these tools to guide medication prescriptions and enhance patient safety.

Understanding Anticholinergic Effects in the Elderly

This review emphasizes the importance of carefully considering anticholinergic burden in older adults, recognizing their increased susceptibility to adverse effects. The authors highlight the need for ongoing research to refine the methods for assessing anticholinergic burden and develop strategies to minimize these risks. The review provides valuable information for healthcare professionals seeking to optimize medication management in older adults.

Navigating Anticholinergic Medications

The review underscores the importance of personalized care and evidence-based decision-making when prescribing medications to older adults. It emphasizes the need to consider the individual patient's overall health status, medication history, and potential risks associated with anticholinergic medications. The review provides valuable insights into the complexities of polypharmacy and the importance of minimizing anticholinergic burden in older adults.

Dr.Camel's Conclusion

As we age, our bodies, like the desert, undergo transformations, becoming more susceptible to the effects of time and environmental factors. Just as a camel's resilience is tested by the harsh desert climate, older adults may experience challenges due to the cumulative effects of medications. This review sheds light on the importance of understanding anticholinergic burden and its potential impact on the elderly. By carefully considering these factors and advocating for personalized care, we can help older adults navigate the complexities of medication management and maintain their well-being.

Date :
  1. Date Completed 2021-11-18
  2. Date Revised 2021-11-18
Further Info :

Pubmed ID

33248197

DOI: Digital Object Identifier

10.1016/j.phrs.2020.105306

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Languages

English

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