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Belatacept associated - cytomegalovirus retinitis in a kidney transplant recipient: a case report and review of the literature.

Author: ArndtCarl, BastienJustine, DeliègePierre-Guillaume, Guyot-ColosioCharlotte, MokriLaetitia, RieuPhilippe

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

A 76-year-old kidney transplant recipient developed multidrug-resistant cytomegalovirus (CMV) retinitis, a serious opportunistic infection that can lead to blindness. The patient had received belatacept, an immunosuppressant medication, and experienced several episodes of CMV reactivation after its introduction. After treatment with various medications, the patient's CMV DNA became undetectable and his visual acuity partially improved. This case suggests that kidney transplant recipients treated with belatacept may be at increased risk for CMV disease, particularly CMV retinitis.
Paper Details　
Original Abstract of the Article :
BACKGROUND: To report the first case of belatacept-associated multidrug-resistant Cytomegalovirus retinitis in a kidney transplant recipient. CASE PRESENTATION: A 76-year-old African male renal allograft recipient was admitted for acute visual loss of the right eye. Ophthalmological examination of ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708192/

データ提供：米国国立医学図書館（NLM）

Belatacept-Associated Cytomegalovirus Retinitis: A Case Report and Review of the Literature

Cytomegalovirus (CMV) retinitis is a serious opportunistic infection that can occur in transplant recipients. This research reports a case of multidrug-resistant CMV retinitis in a kidney transplant recipient treated with belatacept, an immunosuppressant medication. The study reviews the literature on belatacept-associated CMV disease, highlighting the potential increased risk of CMV retinitis in patients receiving this medication. The case report and literature review underscore the importance of careful monitoring for CMV disease in belatacept-treated patients, potentially leading to improved patient management strategies.

Belatacept and CMV Retinitis: A Potential Association

The case report and literature review raise concerns about a potential association between belatacept and CMV retinitis in kidney transplant recipients. The findings highlight the importance of vigilance in monitoring for CMV disease in patients receiving belatacept, potentially leading to earlier diagnosis and treatment, and ultimately improved patient outcomes. This understanding is crucial for optimizing the management of immunosuppression in transplant recipients.

A Camel's View on CMV Retinitis

CMV retinitis can be a formidable foe, akin to a sandstorm threatening a camel's vision in the desert. This research reveals a potential link between belatacept and CMV retinitis, emphasizing the importance of vigilant monitoring for this condition in patients receiving this immunosuppressant. By keeping a close eye on potential threats, healthcare providers can effectively protect their patients from the dangers of this opportunistic infection.

Dr.Camel's Conclusion

This case report and literature review raise awareness about a potential association between belatacept and CMV retinitis in kidney transplant recipients. The findings highlight the importance of vigilant monitoring for CMV disease in these patients, potentially leading to earlier diagnosis and treatment, and ultimately improved patient outcomes.

Date :
  1. Date Completed 2021-05-14
  2. Date Revised 2021-05-14
Further Info :

Pubmed ID

33256663

DOI: Digital Object Identifier

PMC7708192

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SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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