Primaquine overdose in a toddler.

Author: PomeranzElaine, PonceDaphne Morrison, SchaefferWilliam, ViscloskyTimothy

Paper Details 
Original Abstract of the Article :
Antimalarial medications carry a risk of rare, but serious side effects. Primaquine in particular is known to cause methemoglobinemia and hemolytic anemia. In patients with underlying glucose-6-phosphate dehydrogenase (G6PD) deficiency, these side effects become amplified and can be life-threatening...See full text at original site
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引用元:
https://doi.org/10.1016/j.ajem.2020.10.084

データ提供:米国国立医学図書館(NLM)

Primaquine Overdose in a Toddler: A Case of Methemoglobinemia and Hemolytic Anemia

This case report describes a rare and potentially life-threatening situation involving a toddler who accidentally overdosed on primaquine, an antimalarial medication. It's like a desert mirage, revealing a hidden danger in the seemingly safe world of medication. The researchers present a unique case of a patient with undiagnosed glucose-6-phosphate dehydrogenase (G6PD) deficiency who experienced severe methemoglobinemia and hemolytic anemia after primaquine overdose.

Primaquine Overdose: A Potential for Severe Complications

This case report highlights the potential for serious complications, including methemoglobinemia and hemolytic anemia, following primaquine overdose, especially in individuals with G6PD deficiency. It's like a hidden trap in the desert, revealing the importance of careful monitoring and appropriate management of drug-related complications. The case underscores the need for a high index of suspicion and prompt intervention to prevent life-threatening consequences.

Managing Primaquine Overdose: A Complex Challenge

This case demonstrates the complexities of managing primaquine overdose, particularly in patients with G6PD deficiency. It's like navigating a sandstorm in the desert, requiring quick thinking and careful decision-making to address the unique challenges of this situation. The case emphasizes the need for a multidisciplinary approach involving pediatricians, pharmacists, and other healthcare professionals to ensure effective patient care.

Dr.Camel's Conclusion

This case report serves as a reminder that even seemingly safe medications can pose significant risks, especially in vulnerable populations like children. It's a call to action for healthcare professionals to be vigilant in monitoring patients, understanding drug interactions, and responding quickly to potential complications. By embracing a proactive approach to patient care, we can minimize the risk of adverse drug events and ensure the safety of our patients.

Date :
  1. Date Completed 2021-08-25
  2. Date Revised 2021-08-25
Further Info :

Pubmed ID

33279327

DOI: Digital Object Identifier

10.1016/j.ajem.2020.10.084

Related Literature

SNS
PICO Info
in preparation
Languages

English

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