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Rare but life-threatening aspiration pneumonia related to initiation of clobazam therapy.

Author: AungThandar, ShvartsVladimir

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.

Overview

This report highlights the potential for clobazam (CLB), an anti-epileptic medication, to increase drooling and somnolence in patients, leading to an increased risk of aspiration pneumonia. The authors emphasize the need for vigilance in monitoring patients with predisposing factors for aspiration, particularly those receiving CLB treatment.
Paper Details　
Original Abstract of the Article :
Clobazam (CLB) was approved in October 2011 by the United States FDA as an adjunctive therapy for the treatment of seizures associated with Lennox-Gastaut syndrome (LGS) in patients older than the age of 2. Due to its unique chemical design and selective binding to the alpha-2 GABA-receptor, CLB has...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720012/

データ提供：米国国立医学図書館（NLM）

Clobazam and Aspiration Pneumonia: A Desert of Unexpected Challenges

This study explores a hidden danger in the desert of epilepsy treatment: clobazam-induced aspiration pneumonia. The authors, like vigilant desert explorers, uncover a potential complication associated with [treatment], highlighting the need for increased awareness and proactive measures to prevent this serious condition. The authors utilized a [research method] approach to investigate this unexpected finding, offering valuable insights for clinicians treating patients with epilepsy.

A Hidden Oasis of Risk

The study revealed [key findings], highlighting a previously under-recognized risk associated with clobazam therapy. These findings underscore the importance of vigilance and proactive measures to prevent this potentially serious complication.

A Desert Oasis of Safety

This research emphasizes the importance of [recommendations for action] to mitigate the risk of aspiration pneumonia in patients receiving clobazam therapy. It's like finding a hidden oasis in the desert, offering a safe haven from the dangers of this potential complication and providing valuable guidance for ensuring the safety and well-being of patients with epilepsy.

Dr.Camel's Conclusion

While clobazam can be a valuable treatment for epilepsy, this study serves as a reminder of the potential for unexpected complications. It highlights the importance of careful monitoring, proactive measures, and increased awareness among clinicians to ensure the safety and well-being of patients receiving this medication. It's like a hidden oasis of safety in the vast desert of epilepsy treatment, reminding us that even in familiar territory, there can be hidden dangers that we must be aware of.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-12-16
Further Info :

Pubmed ID

33313501

DOI: Digital Object Identifier

PMC7720012

Related Literature

Article Analysis
・Side Effects of clobazam
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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