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Effects of perampanel on cognition and quantitative electroencephalography in patients with epilepsy.

Author: AhnSeon-Jae, ByunJung-Ick, ChaKwang Su, ChuKon, JangIn-Jin, JunJin-Sun, JungKi-Young, KimTae-Joon, LeeSang Kun, LeeSeungHwan, ShinYong-Won, SunwooJun-Sang, YuKyung-Sang

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Perampanel, an antiepileptic drug, showed improvements in delayed recall of the Rey Complex Figure in patients with epilepsy but did not affect other cognitive function tests. It also induced electrophysiological slowing, which correlated with the drug level in blood.
Paper Details　
Original Abstract of the Article :
Antiepileptic drugs are well known for their effects on cognition and electrophysiologic changes. However, perampanel is yet to be evaluated for its effects on cognitive function and electroencephalography (EEG). The purpose of the present study was to identify the effect of perampanel on neuropsych...See full text at original site
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引用元：
https://doi.org/10.1016/j.yebeh.2020.107514

データ提供：米国国立医学図書館（NLM）

Effects of Perampanel on Cognition and Quantitative Electroencephalography in Patients with Epilepsy

This research delves into the effects of a drug called perampanel on patients with epilepsy. It's like a desert explorer seeking to understand the intricate workings of the brain and how to best manage a challenging neurological condition. The researchers investigated the impact of perampanel on cognitive function and brain activity, measured by quantitative electroencephalography (QEEG).

Perampanel and its Effects on Cognition and EEG

The researchers found that perampanel did not significantly impair cognitive function, but it did slow down brain activity, as measured by QEEG. This is like a camel caravan traveling at a slower pace to conserve energy and navigate through challenging terrain.

Importance of Understanding Drug Effects on Epilepsy

This research is important for understanding the effects of antiepileptic drugs on brain function. It's like discovering a new oasis, offering a better understanding of how to manage epilepsy effectively while minimizing negative side effects.

Dr.Camel's Conclusion

This research provides valuable insights into the effects of perampanel on cognition and brain activity in patients with epilepsy. It's a reminder that even in the desert of neurological disorders, there are pathways to better understanding and treatment.

Date :
  1. Date Completed 2021-04-19
  2. Date Revised 2021-12-04
Further Info :

Pubmed ID

33328106

DOI: Digital Object Identifier

10.1016/j.yebeh.2020.107514

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Languages

English

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