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Co-delivery of 5-fluorodeoxyuridine and doxorubicin via gold nanoparticle equipped with affibody-DNA hybrid strands for targeted synergistic chemotherapy of HER2 overexpressing breast cancer.
Author: DuJie, HanMengnan, LiWei, WangXuming, ZhangChao, ZhangFanghua, ZhangHonglei
Original Abstract of the Article :
Combination chemotherapy is still of great importance as part of the standard clinical care for patients with HER2 positive breast cancer. As an attractive component, gold nanoparticles (AuNPs) have been extensively studied as biosafety nanomaterials, but they are rarely explored as drug nanocarrier...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745031/
データ提供:米国国立医学図書館(NLM)
Targeted Synergistic Chemotherapy for HER2 Overexpressing Breast Cancer
The battle against [HER2-positive breast cancer] is a complex and challenging one, with researchers constantly seeking innovative and effective treatment strategies. This study explores the potential of [gold nanoparticles (AuNPs)] as drug nanocarriers for targeted co-delivery of [5-fluorodeoxyuridine (FUdR) and doxorubicin (Dox)] - two potent chemotherapeutic agents. The researchers, like skilled alchemists, have designed a novel approach to combine these drugs, harnessing the power of AuNPs to enhance their effectiveness and specificity. This research, like a hidden oasis in the desert of cancer treatment, offers a promising new avenue for battling HER2-positive breast cancer.
Nano-Sized Warriors: The Potential of AuNPs for Targeted Chemotherapy
This study, like a shimmering oasis in the desert of cancer research, reveals the remarkable potential of AuNPs as a novel tool for targeted chemotherapy. The researchers, like skilled artisans, have crafted these nanoparticles to deliver two potent chemotherapeutic agents directly to HER2-overexpressing breast cancer cells. This targeted delivery system, like a precision-guided missile, promises to enhance the efficacy of these drugs while minimizing their harmful effects on healthy cells. This research, like a beacon of hope, shines a light on the future of cancer treatment, where nanotechnology plays a crucial role in delivering personalized and effective therapies.
A New Frontier in Cancer Treatment: Harnessing the Power of Nanotechnology
This study, like a sunrise over the desert, heralds a new era in cancer treatment. The development of AuNPs as drug nanocarriers for targeted chemotherapy represents a significant advancement in the fight against HER2-positive breast cancer. This research, like a well-equipped caravan, provides clinicians with innovative tools and strategies to combat this challenging disease, offering hope for improved patient outcomes and a future where cancer is no longer a death sentence.
Dr.Camel's Conclusion
This study offers a compelling demonstration of the power of nanotechnology in cancer treatment. The development of AuNPs as drug nanocarriers for targeted delivery of chemotherapeutic agents represents a significant breakthrough in the fight against HER2-positive breast cancer. This research, like a beacon of hope in the desert of cancer research, shines a light on the future of personalized and effective therapies.
Date :
- Date Completed 2021-09-09
- Date Revised 2021-09-09
Further Info :
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