Recent Advances on Epidermal Growth Factor Receptor as a Molecular Target for Breast Cancer Therapeutics.

Author: BeraTanya, DasAmitava, ShettySwathi R, YeeravalliRagini

Paper Details 
Original Abstract of the Article :
Epidermal Growth Factor Receptor (EGFR), a type-I transmembrane protein with intrinsic tyrosine kinase activity, is activated by peptide growth factors such as EGF, epigen, amphiregulin, etc. EGFR plays a vital role in regulating cell growth, migration, and differentiation in various tissue-specific...See full text at original site
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引用元:
https://doi.org/10.2174/1871520621666201222143213

データ提供:米国国立医学図書館(NLM)

Targeting EGFR: A New Frontier in Breast Cancer Therapy

This review focuses on the epidermal growth factor receptor (EGFR), a protein that plays a crucial role in cell growth and survival, and its implications for breast cancer treatment. EGFR is often overexpressed in breast cancer cells, contributing to tumor growth and spread. The review discusses the various approaches being developed to inhibit EGFR activity, including tyrosine kinase inhibitors and monoclonal antibodies, with the aim of developing more effective therapies for breast cancer.

EGFR: A Promising Target for Breast Cancer Treatment

The review highlights the potential of targeting EGFR as a strategy for treating breast cancer. By inhibiting EGFR activity, researchers hope to slow down tumor growth, prevent metastasis, and improve overall patient outcomes. This approach is particularly promising for certain types of breast cancer where EGFR is highly expressed.

Personalized Medicine: A Key to Effective Cancer Treatment

This review underscores the need for personalized medicine in cancer treatment. By understanding the specific molecular characteristics of a tumor, including EGFR expression levels, doctors can tailor treatment strategies to maximize effectiveness and minimize side effects. This individualized approach holds great promise for improving patient outcomes and ultimately, conquering this challenging disease.

Dr. Camel's Conclusion

This review takes us on a journey into the heart of breast cancer research, exploring the potential of targeting EGFR to develop more effective therapies. It's like searching for a hidden oasis in the vast desert of cancer research, offering a potential path towards better treatment options and hope for a brighter future.

Date :
  1. Date Completed 2022-01-17
  2. Date Revised 2022-01-17
Further Info :

Pubmed ID

33355057

DOI: Digital Object Identifier

10.2174/1871520621666201222143213

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English

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