Potency of Tokishakuyakusan in treating preeclampsia: Drug repositioning method by in vitro screening of the Kampo library.

Author: EndoMasayuki, KakiganoAiko, KawanishiYoko, KimuraTadashi, MatsuyamaTatsuya, MimuraKazuya, NakamuraHitomi, TomimatsuTakuji, YagiKazunobu

Paper Details 
Original Abstract of the Article :
INTRODUCTION: Preeclampsia therapy has not been established, except for the termination of pregnancy. The aim of this study was to identify a potential therapeutic agent from traditional Japanese medicine (Kampo) using the drug repositioning method. MATERIALS AND METHODS: We screened a library of 7...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773249/

データ提供:米国国立医学図書館(NLM)

A Kampo Remedy for Preeclampsia: A New Oasis in the Desert

Preeclampsia, a serious pregnancy complication, can be a daunting challenge, much like navigating a treacherous desert. Current treatments for this condition are limited, emphasizing the need for new therapeutic options. This study, like a resourceful explorer seeking a hidden oasis, investigates the potential of Tokishakuyakusan (TS), a traditional Japanese medicine (Kampo), as a treatment for preeclampsia. The authors found that TS significantly increases placental growth factor (PlGF) production, which is known to play a crucial role in promoting angiogenesis, a process essential for healthy pregnancy. This discovery, like finding a hidden spring in a parched desert, offers a promising new strategy for managing preeclampsia.

A Traditional Remedy with Modern Promise

The study's findings suggest that TS, a traditional Japanese medicine, may hold promise as a treatment for preeclampsia. The authors' findings, carefully analyzed and interpreted, demonstrate the potential of TS to increase PlGF production, a crucial factor in maintaining a healthy pregnancy. This discovery, like unearthing a forgotten artifact, reveals the hidden potential of traditional medicine in addressing modern healthcare challenges.

Hope for Preeclampsia Management

The study's findings provide a glimmer of hope for women facing the challenges of preeclampsia. By highlighting the potential of TS as a therapeutic agent, this research opens doors for new approaches to managing this complex condition. This discovery, much like finding a safe haven in a vast and unforgiving desert, offers a promising path towards improving pregnancy outcomes for women at risk for preeclampsia.

Dr. Camel's Conclusion

In the desert of preeclampsia research, this study represents a significant discovery. The authors have unearthed the potential of a traditional Japanese medicine, Tokishakuyakusan, to address this challenging condition. By increasing PlGF production, TS offers a promising new strategy for promoting angiogenesis and improving pregnancy outcomes. This research, like a well-placed oasis, provides much-needed hope for women facing the challenges of preeclampsia.

Date :
  1. Date Completed 2021-03-22
  2. Date Revised 2021-03-22
Further Info :

Pubmed ID

33378412

DOI: Digital Object Identifier

PMC7773249

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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