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Potency of Tokishakuyakusan in treating preeclampsia: Drug repositioning method by in vitro screening of the Kampo library.
Author: EndoMasayuki, KakiganoAiko, KawanishiYoko, KimuraTadashi, MatsuyamaTatsuya, MimuraKazuya, NakamuraHitomi, TomimatsuTakuji, YagiKazunobu
Original Abstract of the Article :
INTRODUCTION: Preeclampsia therapy has not been established, except for the termination of pregnancy. The aim of this study was to identify a potential therapeutic agent from traditional Japanese medicine (Kampo) using the drug repositioning method. MATERIALS AND METHODS: We screened a library of 7...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773249/
データ提供:米国国立医学図書館(NLM)
A Kampo Remedy for Preeclampsia: A New Oasis in the Desert
Preeclampsia, a serious pregnancy complication, can be a daunting challenge, much like navigating a treacherous desert. Current treatments for this condition are limited, emphasizing the need for new therapeutic options. This study, like a resourceful explorer seeking a hidden oasis, investigates the potential of Tokishakuyakusan (TS), a traditional Japanese medicine (Kampo), as a treatment for preeclampsia. The authors found that TS significantly increases placental growth factor (PlGF) production, which is known to play a crucial role in promoting angiogenesis, a process essential for healthy pregnancy. This discovery, like finding a hidden spring in a parched desert, offers a promising new strategy for managing preeclampsia.
A Traditional Remedy with Modern Promise
The study's findings suggest that TS, a traditional Japanese medicine, may hold promise as a treatment for preeclampsia. The authors' findings, carefully analyzed and interpreted, demonstrate the potential of TS to increase PlGF production, a crucial factor in maintaining a healthy pregnancy. This discovery, like unearthing a forgotten artifact, reveals the hidden potential of traditional medicine in addressing modern healthcare challenges.
Hope for Preeclampsia Management
The study's findings provide a glimmer of hope for women facing the challenges of preeclampsia. By highlighting the potential of TS as a therapeutic agent, this research opens doors for new approaches to managing this complex condition. This discovery, much like finding a safe haven in a vast and unforgiving desert, offers a promising path towards improving pregnancy outcomes for women at risk for preeclampsia.
Dr. Camel's Conclusion
In the desert of preeclampsia research, this study represents a significant discovery. The authors have unearthed the potential of a traditional Japanese medicine, Tokishakuyakusan, to address this challenging condition. By increasing PlGF production, TS offers a promising new strategy for promoting angiogenesis and improving pregnancy outcomes. This research, like a well-placed oasis, provides much-needed hope for women facing the challenges of preeclampsia.
Date :
- Date Completed 2021-03-22
- Date Revised 2021-03-22
Further Info :
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