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Urodynamic effectiveness of a beta-3 adrenoreceptor agonist (vibegron) for a pediatric patient with anticholinergic-resistant neurogenic detrusor overactivity: a case report.

Author: HayashiYutaro, KatoTaiki, MizunoKentaro, NishioHidenori, YasuiTakahiro

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This case report describes the use of vibegron, a selective beta-3 adrenoreceptor agonist, to treat anticholinergic-resistant neurogenic detrusor overactivity (NDO) in a young girl with tethered cord syndrome following myelomeningocele repair.
Paper Details　
Original Abstract of the Article :
Myelomeningocele, which causes a neurogenic bladder, is usually treated with anticholinergics in children with neurogenic detrusor overactivity (NDO); however, anticholinergics cause side effects such as dry mouth, constipation, attention deficit, and inadequate reduction in detrusor leak point pres...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890608/

データ提供：米国国立医学図書館（NLM）

Neurogenic Detrusor Overactivity: A Case Study in Pediatric Urodynamics

The field of pediatrics often presents unique challenges, and neurogenic bladder disorders are no exception. This case report explores the urodynamic effectiveness of vibegron, a beta-3 adrenoreceptor agonist, in a pediatric patient with anticholinergic-resistant neurogenic detrusor overactivity (NDO). This research, like a pediatric urologist carefully observing the intricacies of a child's urinary system, delves into the potential benefits of a novel treatment approach.

Vibegron: A Potential Solution for Resistant NDO

The case report suggests that vibegron may be an effective treatment option for pediatric patients with anticholinergic-resistant NDO. This discovery, like finding a new spring of water in the desert, offers hope for those struggling to find relief from this debilitating condition. Further research is needed to confirm the efficacy and safety of vibegron in this population.

Navigating the Urinary Landscape

This case study emphasizes the importance of exploring alternative treatment options for pediatric patients with NDO. It reminds us that just as a desert explorer needs to be resourceful in finding solutions, clinicians need to be innovative in seeking effective therapies for these challenging conditions.

Dr.Camel's Conclusion

This case report presents a promising avenue for treating anticholinergic-resistant NDO in pediatric patients. It's like discovering a new oasis in the desert of pediatric urology, offering a potential solution for a challenging condition. While more research is needed, this research offers a beacon of hope for those seeking effective treatment options for this debilitating condition.

Date :
  1. Date Completed 2021-05-14
  2. Date Revised 2021-05-14
Further Info :

Pubmed ID

33602290

DOI: Digital Object Identifier

PMC7890608

SNS
PICO Info
in preparation
Languages

English

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