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Levetiracetam, perampanel, and the issue of aggression: A self-report study.
Author: BrandFiona, HelmstaedterChristoph, MeschedeCarolin, von WredeRandi
Original Abstract of the Article :
This study investigated to which degree levetiracetam (LEV) and perampanel (PER), antiseizure medications (ASM) that are both known to cause aggression and irritability, share the same or different, behavioral side-effect profiles. In this self-report study, 68 participants with epilepsy treated wit...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.yebeh.2021.107806
データ提供:米国国立医学図書館(NLM)
Levetiracetam and Perampanel: Navigating the Side Effects of Antiepileptic Medications
Epilepsy is a complex neurological disorder, and patients often rely on antiepileptic medications to manage seizures. However, these medications can have side effects, including aggression and irritability. This study investigates the behavioral side effects of two common antiepileptic medications, levetiracetam (LEV) and perampanel (PER).
The study employed a self-report design, asking 68 patients with epilepsy to rate their behavioral experiences with LEV or PER. The analysis revealed that both LEV and PER were associated with negative behavioral changes, but LEV appeared to have a broader impact on behavior, affecting cognition, mood, and physical domains. PER, on the other hand, seemed to specifically induce aggression and irritability.
Understanding the Nuances of Side Effects
The study highlights the importance of understanding the specific side effects associated with different antiepileptic medications. This knowledge can help healthcare professionals tailor treatment plans to minimize adverse effects and optimize patient outcomes. It's a delicate balance, like navigating a shifting desert landscape, where understanding the nuances of the terrain is crucial for safe passage.
Managing the Side Effects of Antiepileptic Medications
This study underscores the need for open communication between patients and healthcare professionals about the potential side effects of antiepileptic medications. By understanding the specific side effects associated with each medication, patients and doctors can work together to develop effective management strategies that minimize adverse effects. This approach is essential for improving the quality of life for individuals with epilepsy.
Dr.Camel's Conclusion
This study offers valuable insights into the behavioral side effects of two common antiepileptic medications. It emphasizes the importance of individualized treatment plans and open communication about potential side effects. As a seasoned desert traveler, I always seek to understand the intricacies of the terrain I am navigating, whether it's the human body or the vast expanse of the desert.
Date :
- Date Completed 2021-04-20
- Date Revised 2021-12-04
Further Info :
Related Literature
English
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