Paper Details 
Original Abstract of the Article :
This study investigated to which degree levetiracetam (LEV) and perampanel (PER), antiseizure medications (ASM) that are both known to cause aggression and irritability, share the same or different, behavioral side-effect profiles. In this self-report study, 68 participants with epilepsy treated wit...See full text at original site
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引用元:
https://doi.org/10.1016/j.yebeh.2021.107806

データ提供:米国国立医学図書館(NLM)

Levetiracetam and Perampanel: Navigating the Side Effects of Antiepileptic Medications

Epilepsy is a complex neurological disorder, and patients often rely on antiepileptic medications to manage seizures. However, these medications can have side effects, including aggression and irritability. This study investigates the behavioral side effects of two common antiepileptic medications, levetiracetam (LEV) and perampanel (PER).

The study employed a self-report design, asking 68 patients with epilepsy to rate their behavioral experiences with LEV or PER. The analysis revealed that both LEV and PER were associated with negative behavioral changes, but LEV appeared to have a broader impact on behavior, affecting cognition, mood, and physical domains. PER, on the other hand, seemed to specifically induce aggression and irritability.

Understanding the Nuances of Side Effects

The study highlights the importance of understanding the specific side effects associated with different antiepileptic medications. This knowledge can help healthcare professionals tailor treatment plans to minimize adverse effects and optimize patient outcomes. It's a delicate balance, like navigating a shifting desert landscape, where understanding the nuances of the terrain is crucial for safe passage.

Managing the Side Effects of Antiepileptic Medications

This study underscores the need for open communication between patients and healthcare professionals about the potential side effects of antiepileptic medications. By understanding the specific side effects associated with each medication, patients and doctors can work together to develop effective management strategies that minimize adverse effects. This approach is essential for improving the quality of life for individuals with epilepsy.

Dr.Camel's Conclusion

This study offers valuable insights into the behavioral side effects of two common antiepileptic medications. It emphasizes the importance of individualized treatment plans and open communication about potential side effects. As a seasoned desert traveler, I always seek to understand the intricacies of the terrain I am navigating, whether it's the human body or the vast expanse of the desert.

Date :
  1. Date Completed 2021-04-20
  2. Date Revised 2021-12-04
Further Info :

Pubmed ID

33621813

DOI: Digital Object Identifier

10.1016/j.yebeh.2021.107806

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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