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Treatment of infantile fibrosarcoma associated to an abdominal aortic aneurysm with larotrectinib: a case report.
Author: Alonso GamarraEduardo, Antolín AlvaradoEugenia, Corral SánchezMaría Dolores, Galán GómezVíctor, González Del ValleLuis, Gómez MartínFelipe, López GutiérrezJuan Carlos, Martínez MartínezLeopoldo, Marín ManzanoElena, Plaza López de SabandoDiego, Pozo KreilingerJosé Juan, Pérez-MartínezAntonio, Regojo ZapataRita María, Rubio AparicioPedro, Sastre UrgellesAna, Sánchez TorresAna María
Original Abstract of the Article :
Infantile fibrosarcoma (IFS) is a rare pediatric tumor which often presents the <i>ETV6-NTRK3</i> gene fusion. <i>NTRK3</i> encodes the neurotrophin-3 growth factor receptor tyrosine kinase, a druggable therapeutic target. Selective tropomyosin receptor kinase (TRK) inhibitors, such as larotrectinib...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1080/08880018.2021.1889730
データ提供:米国国立医学図書館(NLM)
A Beacon of Hope: Larotrectinib for Infantile Fibrosarcoma and Abdominal Aortic Aneurysm
Infantile fibrosarcoma (IFS), a rare and aggressive pediatric tumor, poses a significant challenge for clinicians. This study, like a camel navigating a treacherous desert landscape, explores the use of larotrectinib, a selective TRK inhibitor, for the treatment of IFS associated with an abdominal aortic aneurysm.
A Promising New Approach: Larotrectinib's Potential in Treating IFS
The researchers report a case of a newborn diagnosed with IFS and an associated abdominal aortic aneurysm who was successfully treated with larotrectinib. The findings, like a clear path through a sandstorm, demonstrate the potential of larotrectinib as a targeted therapy for IFS, offering a glimmer of hope for patients with this rare and challenging condition.
A New Era for Pediatric Cancer Treatment: Hope for the Future
This case report, like a single oasis in a vast desert, offers a beacon of hope for families facing the daunting diagnosis of IFS. The study's findings highlight the potential of larotrectinib to provide effective and safe treatment for IFS, underscoring the importance of continued research and development of targeted therapies for pediatric cancers.
Dr.Camel's Conclusion
This case report offers a ray of hope for patients with infantile fibrosarcoma and associated abdominal aortic aneurysms. The study's findings highlight the potential of larotrectinib as a targeted therapy for this rare and challenging condition, underscoring the importance of continued research and development in the field of pediatric oncology.
Date :
- Date Completed 2021-07-29
- Date Revised 2021-07-29
Further Info :
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