Therapeutic effects of Lacosamide in a rat model of traumatic brain injury: A histological, biochemical and electroencephalography monitoring study.

Author: AlpaySuheda, AydemirIsıl, ColluFatih, DuransoyYusuf Kurtuluş, KutluNecip, MeteMesut, TugluMehmet İbrahim, UnsalUlkun Unlu, ÖzelHasan Fehmi

Paper Details 
Original Abstract of the Article :
Traumatic Brain Injury (TBI) is a major cause of death and disability worldwide, especially in children and young adults. TBI can be classified based on severity, mechanism or other features. Inflammation, apoptosis, oxidative stress, and ischemia are some of the important pathophys-iological mechan...See full text at original site
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引用元:
https://doi.org/10.1016/j.injury.2021.02.055

データ提供:米国国立医学図書館(NLM)

Lacosamide: A Potential Neuroprotective Agent for Traumatic Brain Injury

This research explores the potential neuroprotective effects of lacosamide, an anticonvulsant medication, in a rat model of traumatic brain injury (TBI). The study investigated the effects of lacosamide on histological, biochemical, and electroencephalographic measures and found evidence suggesting that lacosamide may offer neuroprotection in the context of TBI. The study encourages further research to validate these findings and to explore the potential therapeutic applications of lacosamide for TBI.

A New Path for TBI Treatment

The study highlights the ongoing search for effective treatments for TBI, a devastating condition that can have long-lasting consequences. The researchers investigated the potential of lacosamide, a medication already used for epilepsy and neuropathic pain, to provide neuroprotection in TBI.

Hope for TBI Survivors

This research offers a glimmer of hope for individuals suffering from TBI. The study's findings suggest that lacosamide may have neuroprotective properties, potentially mitigating the damage caused by TBI. However, further research is crucial to confirm these findings and to establish the optimal dosage and administration route for lacosamide in TBI patients.

Dr.Camel's Conclusion

This research demonstrates the incredible potential of scientific discovery to unlock new avenues for treatment and hope. Just as a desert traveler can find solace in a hidden oasis, researchers are constantly searching for ways to alleviate the suffering caused by TBI. This study's findings offer a promising lead, encouraging continued exploration and innovation in the quest for effective treatments for TBI.

Date :
  1. Date Completed 2021-06-17
  2. Date Revised 2021-06-17
Further Info :

Pubmed ID

33714548

DOI: Digital Object Identifier

10.1016/j.injury.2021.02.055

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English

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