Ibrutinib-related uveitis: A report of two severe cases.

Author: BohnMarcela, Bravo-LjubeticLuciano, LeeRichard W J, PetrushkinHarry

Paper Details 
Original Abstract of the Article :
Ibrutinib is a small-molecule drug approved for the treatment of haematological disorders and is known to be associated with visual disturbances, but uveitis has not yet been reported as an adverse effect of this medication. We present two cases of ibrutinib-associated severe uveitis in patients wit...See full text at original site
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引用元:
https://doi.org/10.1177/11206721211001268

データ提供:米国国立医学図書館(NLM)

Two Cases of Ibrutinib-Related Uveitis: A Rare but Serious Side Effect

This research dives into the critical field of pharmacovigilance, specifically focusing on the identification and reporting of a previously undocumented adverse effect of ibrutinib, a medication used in the treatment of hematological disorders. This research utilizes a case report approach to shed light on this rare but potentially serious side effect.

The report details two cases of ibrutinib-associated severe uveitis, a condition characterized by inflammation of the middle layer of the eye, in patients with chronic lymphocytic leukemia. The report highlights the importance of recognizing uveitis as a potential adverse effect of ibrutinib, particularly in patients presenting with visual disturbances.

The study underscores the importance of vigilant monitoring for potential adverse effects, particularly in patients receiving ibrutinib therapy. The findings emphasize the need for prompt diagnosis and management of uveitis to prevent potential vision loss and minimize the impact on patient well-being.

The Importance of Vigilant Monitoring for Adverse Effects in Drug Therapy

This study highlights the importance of vigilant monitoring for adverse effects in drug therapy. The report underscores the need for healthcare providers to be aware of potential side effects, even those that are rare or previously undocumented, and to promptly investigate any concerns raised by patients.

The Need for Continued Research and Reporting of Adverse Drug Effects

This research emphasizes the ongoing need for research and reporting of adverse drug effects. The identification of this rare adverse effect serves as a reminder of the importance of continuous monitoring and evaluation of drug safety to ensure the well-being of patients receiving medication.

Dr. Camel's Conclusion

This research is like a beacon in the vast desert of drug safety, illuminating a previously hidden danger associated with ibrutinib. The authors, like skilled scouts, identify a rare but potentially serious side effect, urging us to remain vigilant in our pursuit of patient safety. It reminds us that the journey towards optimal drug therapy requires constant vigilance and the dedication to uncovering potential risks, ensuring a safer and more effective treatment experience for all.

Date :
  1. Date Completed 2022-07-21
  2. Date Revised 2022-07-21
Further Info :

Pubmed ID

33719653

DOI: Digital Object Identifier

10.1177/11206721211001268

Related Literature

SNS
PICO Info
in preparation
Languages

English

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