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[Antiemetic protocol in oncohematologic polychemotherapy].

Author: BianconciniG, GobbiF, MazzaliF, MoriniA

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

A combination of chlorpheniramine maleate, sulpiride, and 6-methyl-prednisolone was highly effective in preventing chemotherapy-induced nausea and vomiting in 26 patients.
Paper Details　
Original Abstract of the Article :
Authors, in an open and preliminary study, evaluate the beneficial effects on chemotherapy-induced nausea and vomiting of an association of three antiemetic drugs parenterally administered. Twenty-six patients receiving chemotherapy for Lymphomas (195 cycles) were treated with: Chlorpheniramine male...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/3374828

データ提供：米国国立医学図書館（NLM）

Combating Nausea and Vomiting: A Trio of Antiemetics for Chemotherapy

In the realm of oncology, chemotherapy remains a cornerstone of treatment, but it often comes with the unwelcome side effect of nausea and vomiting. Researchers are constantly seeking ways to alleviate these distressing symptoms, and this study investigates a three-drug combination administered parenterally. Like a camel navigating a vast desert, this research seeks to find the oasis of effective antiemetic therapy. The researchers used a combination of chlorpheniramine maleate, sulpiride, and 6-methyl-prednisolone on 26 patients undergoing chemotherapy for lymphomas. The results were quite promising, with 73.1% of patients achieving a complete response and 27.9% experiencing a partial response. No failures were observed. This study highlights the potential benefit of this three-drug regimen, but further randomized trials are needed to confirm these findings.

A Promising New Antiemetic Regimen

The results of this study are encouraging, as they suggest that a combination of chlorpheniramine maleate, sulpiride, and 6-methyl-prednisolone can effectively reduce chemotherapy-induced nausea and vomiting. This could greatly improve the quality of life for cancer patients undergoing treatment.

Navigating the Desert of Chemotherapy Side Effects

If you are a patient undergoing chemotherapy, it's essential to discuss potential side effects, including nausea and vomiting, with your doctor. They can provide you with the best management strategies, including medication options, and help you navigate the journey of treatment.

Dr.Camel's Conclusion

This study offers a glimmer of hope for patients facing the daunting side effects of chemotherapy. While further research is needed to confirm its effectiveness, this three-drug regimen shows promise in alleviating nausea and vomiting. This research emphasizes the importance of ongoing research and the pursuit of new treatments to improve the lives of cancer patients.

Date :
  1. Date Completed 1988-07-05
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

3374828

DOI: Digital Object Identifier

3374828

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in preparation
Languages

Italian

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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