Paper Details
- Home
- Paper Details
Pharmacokinetic interaction between atorvastatin and fixed-dose combination of sofosbuvir/ledipasvir in healthy male Egyptian volunteers.
Author: AbdelazizA E, AbdelkawyK S, AliA A, BelalF, ElbarbryF, ElmekawyH A
Original Abstract of the Article :
Comorbid conditions of heart and liver disorders added to HCV-induced hepatic steatosis make co-administration of statins, and direct-acting antivirals is common in clinical practice. This study aimed to evaluate the pharmacokinetic interaction of atorvastatin and fixed-dose combination of sofosbuvi...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1007/s00228-021-03130-z
データ提供:米国国立医学図書館(NLM)
Navigating the Pharmacokinetic Landscape of Drug Interactions
The human body is a complex network of interwoven pathways, and understanding how medications interact within this network is crucial for safe and effective drug therapy. This study investigates the pharmacokinetic interaction between atorvastatin, a cholesterol-lowering medication, and a fixed-dose combination of sofosbuvir/ledipasvir, a treatment for hepatitis C. The researchers carefully examined the impact of these medications on each other's absorption, distribution, metabolism, and excretion, providing valuable insights into the potential for drug interactions.
A Detailed Look at Drug Dynamics
This research, like a map guiding researchers through the vast desert of pharmacokinetic interactions, offers a detailed look at the dynamic interplay between medications. The findings provide essential knowledge for healthcare providers, allowing them to prescribe medications more safely and effectively.
Implications for Patient Safety
The study highlights the importance of considering potential drug interactions when prescribing medications. The findings underscore the need for careful monitoring and adjustments in drug therapy to ensure patient safety and optimize treatment outcomes.
Dr. Camel's Conclusion
This research, like a beacon of light in the vast desert of drug interactions, sheds light on the complex interplay between medications. The findings provide valuable insights for healthcare providers, allowing them to navigate the intricate pharmacokinetic landscape and ensure patient safety.
Date :
- Date Completed 2021-12-20
- Date Revised 2021-12-20
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.