Palbociclib with letrozole as second-line neo-systemic therapy after failure of neo-adjuvant chemotherapy for luminal type breast cancer: A case report.

Author: ChoiJin Hyuk, JeonChang Wan, JungMinjung, JungSung Ui

Paper Details 
Original Abstract of the Article :
Neo-adjuvant systemic therapy includes endocrine therapy and chemotherapy, which is widely used. Luminal breast cancer is resistant to chemotherapy and is more likely to not respond to chemotherapy before surgery. Palbociclib is a cyclin-dependent kinase 4 and 6 inhibitor. Palbociclib with letrozole...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036054/

データ提供:米国国立医学図書館(NLM)

Palbociclib and Letrozole: A New Route Through the Desert of Breast Cancer

The world of breast cancer treatment, like a vast and challenging desert, is constantly evolving, seeking new pathways to combat this complex disease. This research explores the use of palbociclib, a drug that acts like a skilled desert navigator, targeting specific pathways involved in cancer cell growth. The researchers investigated the potential of combining palbociclib with letrozole, another powerful drug, as a second-line treatment for luminal type breast cancer. The study, like a groundbreaking discovery of a new oasis in the desert, highlights the potential of this combination therapy as a promising treatment approach for patients who have not responded to initial chemotherapy.

A New Oasis for Breast Cancer Treatment

The study's findings, like a beacon of hope in the desert, suggest that the combination of palbociclib and letrozole may be a valuable treatment option for luminal type breast cancer, offering a new path to effective treatment for patients who have not responded to traditional therapies.

Navigating the Sands of Breast Cancer

This research, like a well-equipped caravan traversing the desert, provides valuable insights into the evolving landscape of breast cancer treatment. The findings underscore the importance of continued research and exploration of new drug combinations to find more effective and personalized therapies.

Dr. Camel's Conclusion

This study, like a desert oasis offering a moment of respite, provides a glimpse into the potential of palbociclib and letrozole combination therapy for breast cancer. The findings highlight the need for further research to explore the full potential of this promising treatment approach.

Date :
  1. Date Completed 2021-04-19
  2. Date Revised 2023-01-03
Further Info :

Pubmed ID

33832078

DOI: Digital Object Identifier

PMC8036054

Related Literature

SNS
PICO Info
in preparation
Languages

English

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