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Glucocorticoids are double-edged sword in the treatment of COVID-19 and cancers.

Author: YangRuixin, YuYingyan

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Glucocorticoids are vital steroid hormones with broad applications in medicine. This review discusses the use of glucocorticoids in treating patients with severe or critical COVID-19 and advanced-stage solid tumors, highlighting their benefits and potential side effects. The ongoing controversy surrounding glucocorticoid use in the medical community is also discussed.
Paper Details　
Original Abstract of the Article :
Glucocorticoids are important steroid hormones. As an outstanding scientific discovery, the scientist who discovered glucocorticoids was awarded the Nobel Prize in Physiology and Medicine in 1950. Cortisone (hydrocortisone) is a natural glucocorticoid, which is secreted with circadian rhythm by the ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071771/

データ提供：米国国立医学図書館（NLM）

Glucocorticoids: A Double-Edged Sword in the Treatment of COVID-19 and Cancers

The field of medicine is constantly navigating the complexities of drug therapy, seeking to maximize benefits while minimizing risks. This review article explores the multifaceted role of glucocorticoids, a class of steroid hormones, in the treatment of COVID-19 and advanced-stage cancers. The researchers delve into the potential benefits and drawbacks of using glucocorticoids in these challenging clinical scenarios.

Glucocorticoids: A Complex Therapeutic Landscape

The review article highlights the double-edged nature of glucocorticoids. While they offer significant therapeutic benefits in treating severe infections, allergies, and other medical conditions, their long-term or high-dose use can lead to a range of adverse effects. This complexity underscores the need for careful consideration and individualized treatment approaches when using glucocorticoids.

Glucocorticoids in COVID-19 and Cancer: Navigating the Risks and Benefits

The review article provides valuable insights into the application of glucocorticoids in the treatment of COVID-19 and advanced-stage cancers. The researchers emphasize the importance of weighing the potential benefits against the associated risks, advocating for a careful and individualized approach to treatment. This research serves as a guide for healthcare professionals seeking to optimize the use of glucocorticoids in these challenging clinical settings.

Dr.Camel's Conclusion

This review article on glucocorticoids presents a complex and nuanced perspective on their role in medicine. It's like navigating a treacherous desert path, where the benefits of these powerful drugs are intertwined with potential risks. This research emphasizes the need for careful consideration and individualized treatment plans when utilizing glucocorticoids, ensuring their optimal application in the fight against diseases like COVID-19 and cancer.

Date :
  1. Date Completed 2021-05-20
  2. Date Revised 2023-11-11
Further Info :

Pubmed ID

33907516

DOI: Digital Object Identifier

PMC8071771

Related Literature

Article Analysis
・Side Effects of hydrocortisone
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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