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Computer aided drug discovery review for infectious diseases with case study of anti-Chagas project.
Author: IshidaTakashi, SekijimaMasakazu, YasuoNobuaki
Original Abstract of the Article :
Neglected tropical diseases (NTDs) are parasitic and bacterial infections that are widespread, especially in the tropics, and cause health problems for about one billion people over 149 countries worldwide. However, in terms of therapeutic agents, for example, nifurtimox and benznidazole were develo...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元：
https://doi.org/10.1016/j.parint.2021.102366
データ提供：米国国立医学図書館（NLM）
Computer Aided Drug Discovery: A Speedy Camel's Journey Through the Desert of Diseases
Drug discovery, my friends, is like a long, arduous journey across the vast desert of diseases. It's a process that can take years, and it's expensive! Imagine, 12 to 14 years and $2.6 billion dollars! Now, wouldn't it be great if we had a shortcut, a speedy camel, to guide us through this desert? That's where computer-aided drug discovery (CADD) comes in. It's like a digital oasis, offering faster and more efficient ways to find new treatments. This research delves into CADD, especially for neglected tropical diseases (NTDs) which affect millions across the globe. The researchers showcase the use of various CADD tools, like databases, molecular simulations, and machine learning, to accelerate the discovery of new drugs, particularly for Chagas disease, a debilitating illness affecting over 8 million people.
A Speedy Camel's Journey Through the Desert of Diseases: CADD for Neglected Tropical Diseases
CADD offers hope for overcoming the challenges of drug discovery for neglected tropical diseases like Chagas disease. The researchers highlight how CADD methods like molecular simulations and machine learning can speed up the process, potentially saving years and billions of dollars.
A Speedy Camel's Journey Through the Desert of Diseases: Impact on Global Health
Faster drug discovery, especially for neglected diseases, could mean improved health outcomes for millions around the world. It's like a welcome oasis in the desert of suffering, bringing relief and hope to those most in need.
Dr.Camel's Conclusion
Computer-aided drug discovery (CADD) presents a promising approach to accelerate the development of new treatments for neglected tropical diseases, such as Chagas disease. By utilizing advanced computational methods, CADD can potentially reduce time and cost, leading to faster access to life-changing therapies for those affected by these diseases.
Date :
- Date Completed 2021-09-20
- Date Revised 2021-09-20
Further Info :
Related Literature
English
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