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Erythromycin acistrate and enterocoated pellets of erythromycin base in acute respiratory infections of hospitalized conscripts.

Author: AntikainenR, GordinA, SalmiH A

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Erythromycin acistrate (EA) was as effective as erythromycin base (EB) in treating acute respiratory tract infections but caused significantly less gastrointestinal side effects.
Paper Details　
Original Abstract of the Article :
The efficacy and tolerability of a new erythromycin ester, erythromycin acistrate (EA), and erythromycin base (EB) as enterocoated pellets were studied in 100 conscripts at the Central Military Hospital. The patients were admitted to hospital for acute respiratory tract infection. The dosage of EA w...See full text at original site
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引用元：
https://doi.org/10.1093/jac/21.suppl_d.93

データ提供：米国国立医学図書館（NLM）

Erythromycin Acistrate: A Gentle Approach to Respiratory Infections

This study compares the efficacy and tolerability of two different erythromycin formulations, erythromycin acistrate (EA) and erythromycin base (EB), in treating acute respiratory infections in hospitalized conscripts. The researchers randomly assigned 100 conscripts to receive either EA or EB treatment and monitored their clinical response and side effects.

Erythromycin Acistrate: A More Tolerable Option

The study found that both EA and EB were effective in treating respiratory infections. However, EA was associated with significantly fewer gastrointestinal side effects compared to EB. This finding suggests that EA may be a more tolerable option for patients with sensitive stomachs. Imagine a camel crossing a desert with a heavy load: EA acts like a lighter pack, reducing the burden on the camel and making the journey more comfortable.

Choosing the Right Antibiotic: A Matter of Comfort

This study highlights the importance of considering the potential side effects of antibiotics when choosing a treatment. It also underscores the potential benefits of EA as a less irritating alternative to EB. As a researcher, I am always looking for ways to improve the patient experience and minimize the discomfort associated with medical interventions. It's like finding a smoother path across the desert: EA can help patients navigate the challenges of illness with greater ease and comfort.

Dr. Camel's Conclusion

This research offers valuable insights into the efficacy and tolerability of different erythromycin formulations. The findings suggest that EA may be a preferable option for treating respiratory infections due to its lower incidence of gastrointestinal side effects. As a researcher, I am constantly seeking new ways to improve the treatment of infectious diseases and make the journey through illness more bearable for patients. Just as a camel needs a comfortable saddle and a well-prepared route across the desert, patients deserve treatment options that minimize discomfort and promote healing.
Date :
  1. Date Completed 1988-08-24
  2. Date Revised 2019-05-10
Further Info :

Pubmed ID

3391881

DOI: Digital Object Identifier

10.1093/jac/21.suppl_d.93

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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