Paper Details

  1. Home
  2. Paper Details

Novel 1-L polyethylene glycol + ascorbate versus high-volume polyethylene glycol regimen for colonoscopy cleansing: a multicenter, randomized, phase IV study.

Author: AmataMichele, AnderloniAndrea, AntonelliGiulio, BudaAndrea, CannizzaroRenato, CapogrecoAntonio, CarraraSilvia, CesaroPaola, CorrealeLoredana, Di LeoMilena, FerraraElisa, FinatiElena, FuccioLorenzo, FugazzaAlessandro, GaltieriAlessia, GranataAntonino, GuarnieriGiovanni, HassanCesare, LorenzettiRoberto, MaieroStefania, MannoMauro, MaselliRoberta, Minelli GrazioliLeonardo, OcchipintiPietro, PellegattaGaia, RadaelliFranco, RepiciAlessandro, SpadaCristiano, SpadacciniMarco, TrainaMario, ZulloAngelo

Clinical Trial, Phase IVPost-marketing surveillance. Monitors long-term safety/efficacy after approval.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

One-liter PEG+ASC regimen was noninferior to 4L-PEG in achieving adequate colon cleansing and provided higher patient compliance, with no difference in tolerability or safety.
Paper Details　
Original Abstract of the Article :
BACKGROUND AND AIMS: Adequate bowel cleansing is critical to ensure quality and safety of a colonoscopy. A novel 1-L polyethylene glycol plus ascorbate (1L-PEG+ASC) regimen was previously validated against low-volume regimens but was never compared with high-volume regimens. METHODS: In a phase IV ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.gie.2021.04.020

データ提供：米国国立医学図書館（NLM）

Polyethylene Glycol: A New, Efficient Regimen for Colonoscopy Cleansing

Adequate bowel cleansing is crucial for a successful colonoscopy, but traditional high-volume polyethylene glycol (PEG) regimens can be challenging for patients. This study evaluated a novel 1-L PEG plus ascorbate (1L-PEG+ASC) regimen for colonoscopy cleansing compared to a high-volume 4-L PEG regimen. The study found that the 1L-PEG+ASC regimen achieved non-inferiority to the 4-L PEG regimen in terms of bowel cleansing quality, with a higher patient compliance rate. The 1L-PEG+ASC regimen also demonstrated similar safety and tolerability profiles compared to the 4-L PEG regimen. This study suggests that the 1L-PEG+ASC regimen offers a more patient-friendly and effective option for bowel cleansing prior to colonoscopy.

Polyethylene Glycol: A More Patient-Friendly Approach to Bowel Cleansing

This study highlights the potential of a novel 1-L PEG plus ascorbate (1L-PEG+ASC) regimen to provide a more patient-friendly and effective alternative to traditional high-volume PEG regimens for bowel cleansing prior to colonoscopy. The findings demonstrate that the 1L-PEG+ASC regimen achieves comparable cleansing quality with higher patient compliance, potentially improving the overall experience for patients undergoing colonoscopy.

Polyethylene Glycol: A Smoother Journey for Colonoscopy Patients

Navigating the complexities of bowel preparation for colonoscopy can be a challenging experience. This study provides evidence that a novel 1-L PEG plus ascorbate (1L-PEG+ASC) regimen offers a smoother and more patient-friendly approach, potentially making the entire process less daunting for individuals undergoing colonoscopy.

Dr. Camel's Conclusion

This study provides compelling evidence that a novel 1-L PEG plus ascorbate (1L-PEG+ASC) regimen offers a more patient-friendly and effective alternative to traditional high-volume PEG regimens for bowel cleansing prior to colonoscopy. The findings demonstrate that the 1L-PEG+ASC regimen achieves comparable cleansing quality with higher patient compliance, potentially improving the overall experience for patients undergoing colonoscopy.
Date :
  1. Date Completed 2021-10-15
  2. Date Revised 2022-03-06
Further Info :

Pubmed ID

33940043

DOI: Digital Object Identifier

10.1016/j.gie.2021.04.020

Related Literature

Article Analysis
・Effective treatment of colon cleansing
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.