Is there a role for doravirine in African HIV treatment programmes? A large observational resistance study in South Africa.

Author: HansLucia, MoorhouseMichelle, SteegenKim, VenterWillem Df, WensingAnnemarie Mj

Paper Details 
Original Abstract of the Article :
Dolutegravir has replaced efavirenz in most low- and middle-income countries, due to better tolerability and formidable resistance profile, but dolutegravir side effects suggest alternatives are needed. We evaluated doravirine resistance in South Africa as a first step to assess whether doravirine m...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094661/

データ提供:米国国立医学図書館(NLM)

Doravirine: A Potential Alternative for HIV Treatment in Africa?

The fight against HIV in Africa, like navigating a vast desert, requires innovative strategies and effective treatments. This study explores the potential role of doravirine, an antiretroviral medication, as an alternative to dolutegravir in HIV treatment programs in South Africa.

Evaluating Doravirine Resistance: A Crucial Step in HIV Treatment

Dolutegravir has become the preferred treatment for HIV in many low- and middle-income countries due to its effectiveness and tolerability. However, the study highlights the need for alternative options due to potential side effects associated with dolutegravir. This study evaluates the resistance profile of doravirine in South Africa, providing crucial information for deciding if it can be a viable replacement. It's like searching for a new source of water in a drought-stricken desert, seeking alternatives to ensure continued survival.

Navigating the Complex Landscape of HIV Treatment

This study underscores the importance of ongoing research to identify and evaluate effective treatment options for HIV, particularly in resource-limited settings. It's like mapping a complex desert landscape, identifying new routes and resources to ensure long-term sustainability and well-being.

Dr.Camel's Conclusion

This study investigates the potential of doravirine as a potential alternative to dolutegravir in HIV treatment programs in Africa. The research underscores the importance of identifying effective treatment options, particularly in resource-limited settings. This study, like a camel caravan searching for a new oasis, aims to ensure the continued success of HIV treatment efforts.

Date :
  1. Date Completed 2021-10-15
  2. Date Revised 2022-05-31
Further Info :

Pubmed ID

33943000

DOI: Digital Object Identifier

PMC8094661

Related Literature

SNS
PICO Info
in preparation
Languages

English

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