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Karnofsky Performance Score - An Independent Prognostic Factor of Survival After Palliative Irradiation for Sino-nasal Cancer.

Author: RadesDirk, SchildSteven E, StaackmannChristian

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Karnofsky performance score is an independent predictor of survival for palliative irradiation of sino-nasal cancer. Completion of radiotherapy is important for survival, and patients require close monitoring for side effects.
Paper Details　
Original Abstract of the Article :
BACKGROUND/AIM: Sino-nasal cancer is rare and often diagnosed at advanced stages. Some patients cannot receive curative treatment and are treated with palliative irradiation. We aimed to identify prognostic factors for survival to facilitate treatment personalization for this group. PATIENTS AND ME...See full text at original site
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引用元：
https://doi.org/10.21873/anticanres.15027

データ提供：米国国立医学図書館（NLM）

Karnofsky Performance Score: A Prognostic Factor for Sino-nasal Cancer

This research investigates the prognostic significance of Karnofsky Performance Score (KPS) in patients with locally advanced sino-nasal cancer treated with palliative radiotherapy. The study aimed to identify factors that predict survival in this patient population and to facilitate personalized treatment planning.

The researchers retrospectively analyzed data from 12 patients treated with palliative radiotherapy for sino-nasal cancer, evaluating various characteristics including age, gender, KPS, pre-radiotherapy hemoglobin, tumor site, lymph node involvement, histology, equivalent dose in 2 Gy-fractions, completion of radiotherapy, and concurrent chemotherapy. The results showed that a KPS ≥ 70 was significantly associated with better survival on both univariate and multivariate analysis.

KPS as a Prognostic Indicator in Sino-nasal Cancer

This study provides evidence that KPS is an independent predictor of survival for palliative irradiation of sino-nasal cancer. The findings suggest that KPS can be a valuable tool for assessing prognosis and guiding treatment decisions in this patient population.

Health and Lifestyle: Understanding Cancer Prognosis

Cancer prognosis can vary significantly depending on factors such as the type of cancer, stage of disease, and overall health status. This study highlights the importance of assessing factors like KPS to inform treatment planning and provide realistic expectations for patients.

Dr.Camel's Conclusion

This research, like a camel navigating a treacherous desert path, explores the significance of the Karnofsky Performance Score in predicting outcomes for patients with sino-nasal cancer. The study underscores the importance of using validated tools to assess prognosis and tailor treatment plans to individual needs. It emphasizes the need for continued research to improve our understanding of cancer and develop more effective treatment strategies.

Date :
  1. Date Completed 2021-05-13
  2. Date Revised 2021-05-13
Further Info :

Pubmed ID

33952477

DOI: Digital Object Identifier

10.21873/anticanres.15027

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Languages

English

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