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"The pharmacological profile of SGLT2 inhibitors: Focus on mechanistic aspects and pharmacogenomics".

Author: BeheraBidwan Sekhar, KaurPrabhsimran, MunshiAnjana, SinghSandeep

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review discusses SGLT2 inhibitors, a new class of drugs for treating diabetes. They work by blocking glucose reabsorption in the kidneys, leading to increased glucose excretion in urine. Dapagliflozin, empagliflozin, and canagliflozin are the most widely used SGLT2 inhibitors. They are effective in controlling blood sugar levels with few side effects. However, individual responses and adverse effects may be influenced by genetic variations.
Paper Details　
Original Abstract of the Article :
Diabetes, characterized by high glucose levels, has been listed to be one of the world's major causes of death. Around 1.6 million deaths are attributed to this disease each year. Persistent hyperglycemic conditions in diabetic patients affect various organs of the body leading to diabetic complicat...See full text at original site
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引用元：
https://doi.org/10.1016/j.ejphar.2021.174169

データ提供：米国国立医学図書館（NLM）

SGLT2 Inhibitors for Diabetes: A New Path in the Desert

This research delves into the world of SGLT2 inhibitors, a new class of drugs used to treat diabetes. It's like exploring a desert landscape, seeking out new paths and solutions to a widespread health concern. The authors are examining the mechanisms of action and genetic factors that influence the effectiveness of these drugs.

A New Oasis of Hope: SGLT2 Inhibitors and Diabetes

The study highlights the potential of SGLT2 inhibitors as a new and effective approach to treating diabetes. It's like discovering a hidden oasis in the desert, offering a new source of life and hope for those struggling with this disease. The authors have found that these drugs can effectively control blood glucose levels with minimal side effects.

Finding the Right Path: Personalized Treatment

This research underscores the importance of personalized medicine in diabetes management. It's like navigating a desert landscape, where each path requires a unique approach. By understanding the genetic factors that influence drug response, we can create more effective and personalized treatment plans for individuals with diabetes.

Dr.Camel's Conclusion

This study explores the potential of SGLT2 inhibitors as a new and effective treatment for diabetes. It's like discovering a hidden oasis in the desert, offering a new source of hope and healing for those struggling with this disease. The authors have found that these drugs can effectively control blood glucose levels with minimal side effects, highlighting the importance of personalized medicine in diabetes management.

Date :
  1. Date Completed 2021-11-05
  2. Date Revised 2021-11-05
Further Info :

Pubmed ID

33984301

DOI: Digital Object Identifier

10.1016/j.ejphar.2021.174169

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Languages

English

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